Peptic Ulcer Disease Treatment Using Herbal Plants: Harnessing Ethnobotanical Studies for Clinical Application.
Background: Peptic ulcer disease (PUD) is a major gastrointestinal disorder associated with Helicobacter pylori (H. pylori) infection, nonsteroidal anti‐inflammatory drug (NSAID) use, and impaired mucosal defense. Ethnobotanical studies have revealed that the heavy reliance on medicinal plants as a...
| Publicado en: | Journal of Clinical Pharmacy & Therapeutics Vol. 2026; pp. 1 - 13 |
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| Autores principales: | , , , , , , |
| Formato: | pictorial review tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
3/2/2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=192000740&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 192000740 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 02694727 EV4 jtl: Journal of Clinical Pharmacy & Therapeutics issn: 02694727 maglogo: Y pubinfo: dt: 3/2/2026 vid: 2026 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 192000740 192000740 192000740 10.1155/jcpt/6501202 192000740 ppf: 1 ppct: 12 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Peptic Ulcer Disease Treatment Using Herbal Plants: Harnessing Ethnobotanical Studies for Clinical Application. aug: au: Okoampah, Emmanuel Payne, Joseph Shine, Joan Davids Agyeman, Philomina Ofosuhemaa, Princess Dufailu, Osman A. Raza, Faisal affil: Department of Biochemistry,, Faculty of Biosciences,, University for Development Studies,, Tamale, Ghana, uds.edu.gh sug: subj: Peptic Ulcer Drug Therapy Plants, Medicinal Therapeutic Use Phytochemicals Therapeutic Use Phytochemicals Pharmacodynamics Plant Extracts Pharmacodynamics Phytochemicals Analysis Plant Extracts Analysis Antioxidants Antiinfective Agents Antiinflammatory Agents Flavonoids Tannins Alkaloids Terpenes Helicobacter Infections Drug Therapy Gastrointestinal Motility Drug Effects Omeprazole Administration and Dosage Omeprazole Pharmacodynamics Essential Oils Pharmacodynamics Essential Oils Administration and Dosage Plant Extracts Administration and Dosage Phytochemicals Administration and Dosage ab: Background: Peptic ulcer disease (PUD) is a major gastrointestinal disorder associated with Helicobacter pylori (H. pylori) infection, nonsteroidal anti‐inflammatory drug (NSAID) use, and impaired mucosal defense. Ethnobotanical studies have revealed that the heavy reliance on medicinal plants as a treatment option for ulcers is usually guided by traditional knowledge and normal practice rather than scientific validation. Limitations of the existing conventional therapies have necessitated interest in scientifically evaluating the potential of medicinal plants. Objective: This review integrates ethnobotanical, phytochemical, and experimental evidence on medicinal plants used in PUD management and examines their clinical translation relevance. Methods: Ethnobotanical, in vitro, in vivo, and clinical studies were identified through structured database searches and analyzed for plant species, bioactive compounds, mechanisms, and therapeutic effects. Results: Medicinal plants exhibited antioxidant, anti‐inflammatory, antimicrobial, cytoprotective, and mucosal healing activities, largely mediated by flavonoids, tannins, alkaloids, terpenoids, and saponins. Conclusions: The study has revealed medicinal plants as an ideal candidate for ulceration management. pubtype: Academic Journal doctype: pictorial review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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