Association between short-term heat exposure and herpangina incidence in Japan: a nationwide space-time-stratified case-crossover study.
This study aims to quantify the impact of ambient temperature on the risk of herpangina in Japan. We compiled weekly time-series data on the incidence of herpangina and meteorological factors in all 47 Japanese prefectures (2005–2019). A space-time-stratified case-crossover design, combined with a d...
| Publicado en: | International Journal of Environmental Health Research Vol. 36; no. 3; pp. 405 - 411 |
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| Autor principal: | |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
Mar2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=192005977&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 192005977 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09603123 57L jtl: International Journal of Environmental Health Research issn: 09603123 maglogo: Y pubinfo: dt: Mar2026 vid: 36 iid: 3 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 192005977 186191982 192005977 192005977 10.1080/09603123.2025.2524041 192005977 ppf: 405 ppct: 6 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Association between short-term heat exposure and herpangina incidence in Japan: a nationwide space-time-stratified case-crossover study. aug: au: Wagatsuma, Keita affil: Division of International Health (Public Health), Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan sug: subj: Heat Exhaustion Complications Coxsackievirus Infections Epidemiology Risk Assessment Human Japan Time Series Crossover Design Poisson Distribution Two-Tailed Test Descriptive Statistics Data Analysis Software Confidence Intervals Multivariate Analysis Coxsackievirus Infections Risk Factors ab: This study aims to quantify the impact of ambient temperature on the risk of herpangina in Japan. We compiled weekly time-series data on the incidence of herpangina and meteorological factors in all 47 Japanese prefectures (2005–2019). A space-time-stratified case-crossover design, combined with a distributed lag nonlinear model, was employed to estimate the relative risk (RR) of heat exposure across prefectures. A multivariate meta-analysis was conducted to obtain pooled estimates at the national level. Our analysis revealed a nonlinear, inverted U-shaped association between ambient temperature and the incidence of herpangina at the national level in Japan. Peak risk occurred at 24.3 °C, with an RR of 8.65 (95% confidence interval: 6.32–11.84) relative to the minimal risk. This association was predominantly driven by the immediate effects of high temperatures, with the risk persisting for up to four weeks. Our assessment demonstrates that high temperatures increase the risk of herpangina, highlighting the need for targeted preventive measures to mitigate the health impacts of global warming. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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