Pollen exposure and allergy risk: a systematic review and meta-analysis.

Pollen is a widespread environmental allergen linked to various allergic conditions, including rhinitis and asthma. This systematic review and meta-analysis aimed to evaluate the association between pollen exposure and allergy risk, considering different pollen concentrations, age groups, exposure s...

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Publicado en:International Journal of Environmental Health Research Vol. 36; no. 3; pp. 554 - 569
Autores principales: Berezhanskiy, Pavel V., Mahmoudizeh, Amirhossein, Fakhri, Yadolah
Formato: meta analysis research systematic review tables/charts Journal Article
Publicado: Taylor & Francis Ltd Mar2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Mar2026
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      pub: Taylor & Francis Ltd
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        atl: Pollen exposure and allergy risk: a systematic review and meta-analysis.
      aug:
        au:
          Berezhanskiy, Pavel V.
          Mahmoudizeh, Amirhossein
          Fakhri, Yadolah
        affil: Department of Pediatric Diseases, N.F. Filatov Clinical Institute of Children's Health, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia
      sug:
        subj:
          Pollen Adverse Effects
          Pollen Analysis
          Environmental Exposure Adverse Effects
          Hypersensitivity Risk Factors
          Risk Assessment
          Age Factors
          Geographic Factors
          Human
          Systematic Review
          PubMed
          Embase
          Meta Analysis
          Descriptive Statistics
          Confidence Intervals
          Geographic Locations
          Child
          Adult
          Child: 6-12 years
          Adult: 19-44 years
      ab: Pollen is a widespread environmental allergen linked to various allergic conditions, including rhinitis and asthma. This systematic review and meta-analysis aimed to evaluate the association between pollen exposure and allergy risk, considering different pollen concentrations, age groups, exposure settings, type of study, and geographic regions. Search was conducted in PubMed, Embase, Web of Science, and Scopus from 1 January 2000 to 20 February 2025. The systematic review included 31 papers containing 96 data-reports across 1,942,079 participants. The random-effects model in our meta-analysis was conducted to estimate pool effect sizes (ESs) with 95% confidence intervals (CIs) in pollen concentration, age, exposure setting, country, and study design subgroup. Overall, pollen exposure significantly increased allergy risk (ES: 1.13, 95% CI: 1.11–1.16, I2 = 94.6%). High pollen concentrations (≥200 grains/m3) showed a stronger effect (ES: 1.76, 95% CI: 1.57–1.96) than low concentrations (< 200 grains/m3, ES: 1.07, 95% CI: 1.05–1.10). Children (ES: 1.12, 95% CI: 1.09–1.15) and adults (ES: 1.23, 95% CI: 1.14–1.32) were both significantly affected. Tree and cypress pollen were the most potent allergens. Pollen exposure significantly increases allergy risk, with dose-dependent and demographic variations. High pollen concentrations and specific geographic regions pose greater risks. These findings underscore the need for targeted public health strategies to mitigate pollen-related allergic diseases.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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