Contrast-induced acute kidney injury and nephrogenic systemic fibrosis in children.

Intravascular contrast media plays an important role in improving tissue and vascular characterisation in diagnostic imaging and image-guided intervention. Iodinated contrast media are commonly used in imaging modalities which utilise ionising radiation and gadolinium-based contrast agents (GBCA) in...

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Publicado en:Pediatric Nephrology Vol. 41; no. 4; pp. 957 - 973
Autores principales: Chuah, Alice Ming‑jie, Chen, Jonathan, Ma, Alison Lap‑tak, Fung, Kin Fen Kevin, Chan, Eugene Yu‑hin
Formato: algorithm case study diagnostic images review tables/charts Journal Article
Publicado: Springer Nature Apr2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2026
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      pub: Springer Nature
      place: New York, New York
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        atl: Contrast-induced acute kidney injury and nephrogenic systemic fibrosis in children.
      aug:
        au:
          Chuah, Alice Ming‑jie
          Chen, Jonathan
          Ma, Alison Lap‑tak
          Fung, Kin Fen Kevin
          Chan, Eugene Yu‑hin
        affil: https://ror.org/05wga2g83 Paediatric Unit, Hospital Sultanah Bahiyah, Langgar, Malaysia
      sug:
        subj:
          Contrast Media Adverse Effects
          Kidney Failure, Acute Chemically Induced
          Fibrosis Chemically Induced
          Kidney Failure, Acute Prevention and Control
          Fibrosis Prevention and Control
          Practice Guidelines
          Patient Safety
          Pediatric Care
          Tomography, X-Ray Computed
          Magnetic Resonance Imaging
          Glomerular Filtration Rate
          Cystatin C
          Biological Markers
          Kidney Failure, Acute Risk Factors
          Fibrosis Risk Factors
          Nephrotoxicity Prevention and Control
          Kidney Failure, Acute Epidemiology
          Kidney Diseases
          Obesity
          Antibiotics Adverse Effects
          Dehydration
          Cardiovascular Diseases
          Fluid Therapy
          Mannitol Adverse Effects
          Furosemide Adverse Effects
          Acetylcysteine Therapeutic Use
          Algorithms
          Guideline Adherence
          Consensus
          Elements Adverse Effects
          Iodine Compounds Adverse Effects
          Kidney Failure, Acute Physiopathology
          Fibrosis Physiopathology
          Child
          Female
          Male
          Child, Preschool
          Child: 6-12 years
          Child, Preschool: 2-5 years
          Female
          Male
      ab: Intravascular contrast media plays an important role in improving tissue and vascular characterisation in diagnostic imaging and image-guided intervention. Iodinated contrast media are commonly used in imaging modalities which utilise ionising radiation and gadolinium-based contrast agents (GBCA) in magnetic resonance imaging. Intravascular use of iodinated contrast medium is associated with contrast-induced acute kidney injury and GBCA with nephrogenic systemic fibrosis, both of which can lead to potentially significant adverse outcomes in patients with kidney impairment. However, most studies in the literature focus on adults and the evidence in the paediatric population is scarce. In this review, we aim to examine the consensus guidelines and studies in the paediatric population who require intravascular iodinated contrast media and GBCA. At the end, we propose an algorithm to approach the use of intravascular contrast media in children who need to undergo diagnostic imaging or image-guided intervention.
      pubtype: Academic Journal
      doctype:
        algorithm
        case study
        diagnostic images
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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