Research Progress on the Regulatory Mechanism of Respiratory Microbiota in the Comorbidity of Chronic Obstructive Pulmonary Disease and Lung Cancer.
Both chronic obstructive pulmonary disease (COPD) and lung carcinoma (LC) are major public health challenges in China. With the continuous advancement of microbial detection methods, the role of the respiratory microbiome in the pathogenesis and progression of respiratory diseases has become increas...
| Publicado en: | Chinese Journal of Lung Cancer Vol. 28; no. 12; pp. 939 - 948 |
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| Autores principales: | , , |
| Formato: | pictorial review tables/charts Journal Article |
| Publicado: |
Chinese Journal of Lung Cancer
Dec2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=192018141&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 192018141 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10093419 9014 jtl: Chinese Journal of Lung Cancer issn: 10093419 maglogo: N pubinfo: dt: Dec2025 vid: 28 iid: 12 pid: 54191 pub: Chinese Journal of Lung Cancer artinfo: ui: 192018141 192018141 192018141 10.3779/j.issn.1009-3419.2025.106.33 192018141 ppf: 939 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Research Progress on the Regulatory Mechanism of Respiratory Microbiota in the Comorbidity of Chronic Obstructive Pulmonary Disease and Lung Cancer. aug: au: ZHANG, Yin ZHANG, Tianming WANG, Hong affil: Second Clinical Medical School of Lanzhou University sug: subj: Pulmonary Disease, Chronic Obstructive Microbiology Lung Neoplasms Microbiology Microbiota Disease Progression Comorbidity Inflammation Immunology DNA Damage Immune System Physiology China Respiratory Tract Diseases Physiopathology Microbial Culture and Sensitivity Tests Biological Markers Early Detection of Cancer Cancer Screening Disease Management Genomics ab: Both chronic obstructive pulmonary disease (COPD) and lung carcinoma (LC) are major public health challenges in China. With the continuous advancement of microbial detection methods, the role of the respiratory microbiome in the pathogenesis and progression of respiratory diseases has become increasingly prominent. This article systematically reviews the dynamic characteristics of the respiratory microbiome during the progression of COPD and LC, then explores its crucial bridging role in COPD-LC comorbidity through mechanisms such as persistently driving chronic inflammation, mediating genomic damage, and participating in immune regulation. The aim is to deepen the understanding of the respiratory microbiome, and to provide new perspectives for optimizing existing treatment strategies, exploring microbial biomarkers for early cancer screening, and improving the clinical management of chronic respiratory diseases. pubtype: Academic Journal doctype: pictorial review tables/charts Journal Article ougenre: Article language: Chinese refInfo: holdings: @attributes: islocal: N |
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