Validation of a Pediatric Cognitive Assessment Tool to Advance Knowledge on Children's Cognitive Development, Health Risk Factors, and Health-promoting Interventions in Sub-Saharan Regions.

BACKGROUND: Cognitive Assessment Tool for Pediatric Clinical Research (CAT-PCR) is a new brief nonverbal test battery validated in a Zambian school-aged population. CAT-PCR involves the standardized administration of two tests, WAVES and SYMBOLS. CAT-PCR provides measures of visuomotor processing (V...

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Publicado en:Innovations in Clinical Neuroscience Vol. 22; no. 10-12; pp. 33 - 52
Autores principales: Di Cesare, Franco, Di Carlo, Cristiana, Di Cesare, Leonardo
Formato: research tables/charts Journal Article
Publicado: Matrix Medical Communications, LLC Oct-Dec2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct-Dec2025
      vid: 22
      iid: 10-12
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      pub: Matrix Medical Communications, LLC
      place: West Chester, Pennsylvania
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        atl: Validation of a Pediatric Cognitive Assessment Tool to Advance Knowledge on Children's Cognitive Development, Health Risk Factors, and Health-promoting Interventions in Sub-Saharan Regions.
      aug:
        au:
          Di Cesare, Franco
          Di Carlo, Cristiana
          Di Cesare, Leonardo
        affil: All authors are with Leoben Research Aurora in San Vincenzo Valle Roveto (AQ), Italy.
      sug:
        subj:
          Clinical Assessment Tools Evaluation
          Health Knowledge Evaluation
          Cognition Evaluation
          Child Development Evaluation
          Cognition Disorders Risk Factors
          Risk Assessment
          Health Promotion Zambia
          Research, Mental Health
          Instrument Validation
          Reliability and Validity Evaluation
          Instrument Construction
          Human
          Male
          Female
          Child
          Validation Studies
          Africa South of the Sahara
          Psychometrics
          Visual Perception
          Test-Retest Reliability
          Health Status
          Mental Health
          Stress, Psychological
          Intraclass Correlation Coefficient
          Purposive Sample
          Socioeconomic Factors
          Culture
          Linguistics
          Memory Evaluation
          Predictive Validity
          Sensitivity and Specificity
          Sex Factors
          Factor Analysis
          Internal Consistency
          Confidence Intervals
          Age Factors
          Child, Preschool
          Zambia
          Funding Source
          Cross Sectional Studies
          Adolescence
          Task Performance and Analysis
          Communication Skills
          Reproducibility of Results
          Structured Interview
          Questionnaires
          Descriptive Statistics
          Data Analysis Software
          Construct Validity
          Logistic Regression
          Chi Square Test
          Nonparametric Statistics
          Parametric Statistics
          One-Way Analysis of Variance
          Two-Way Analysis of Variance
          Post Hoc Analysis
          Child: 6-12 years
          Child, Preschool: 2-5 years
          Adolescent: 13-18 years
          Male
          Female
      ab: BACKGROUND: Cognitive Assessment Tool for Pediatric Clinical Research (CAT-PCR) is a new brief nonverbal test battery validated in a Zambian school-aged population. CAT-PCR involves the standardized administration of two tests, WAVES and SYMBOLS. CAT-PCR provides measures of visuomotor processing (VMP) and visuographomotor constructional processing (VGCP). The psychometric properties of CAT-PCR were evaluated in a field trial complemented with an ancillary test-retest study. RESULTS: Four-hundred-twenty children, aged 5 to 17 years, 51.2 percent female, speaking Bemba (81.1%), English (72.6 %), Nyanja (22.8%), Tonga (1.9%), and Lozi (1.2%), were recruited at multiple Zambian clinical sites and schools. Children able to speak one, two, and three or more languages composed 23.5, 10.0, and 66.5 percent of participants, respectively. CAT-PCR detected differences in cognitive performance between two comparable subgroups of children with or without conditions associated with increased risk for cognitive impairment. The poorer health group composition reflected a spectrum of conditions such as chronic neurologic or medical diseases (ie, epilepsy, human immunodeficiency virus/acquired immunodeficiency syndrome [HIV/AIDS], recurrent malaria, sickle cell disease, and other cardiac and metabolic conditions) or prolonged exposure to psychosocial stress and deprivation. The reliability was satisfactory. The intraclass correlation coefficient (95% confidence interval) at test-retest at 48 hours (n=86) was 0.85 (0.78, 0.91) for VGCP Index and 0.84 (0.76, 0.90) for VMP Index. CONCLUSION: Study findings support the reliability, validity, and utility of CAT-PCR measures in evaluating the effect of health-related risks on the child's cognitive functioning and development. Further research should address the validity of CAT-PCR in response prediction, monitoring, and evaluation of health-promoting interventions.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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