Medication Adherence and Its Determinants Among Adults With Heart Failure: A Study in Selected Hospitals of North Shewa Zone, Oromia, Ethiopia (2024)—A Multicenter Institutional-Based Cross-Sectional Study.
Background: Effective management of heart failure (HF) critically relies on adherence to evidence-based pharmacotherapy. However, adherence remains suboptimal, contributing to preventable hospital readmissions, disease progression, and increased healthcare costs. This study assessed medication adher...
| Publicado en: | Advances in Rehabilitation Science & Practice Vol. 15; pp. 1 - 11 |
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| Autores principales: | , , , , , , |
| Formato: | equations & formulas research tables/charts Journal Article |
| Publicado: |
Sage Publications Inc.
3/10/2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=192230560&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 192230560 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 27536351 N7A5 jtl: Advances in Rehabilitation Science & Practice issn: 27536351 maglogo: Y pubinfo: dt: 3/10/2026 vid: 15 pid: 344 pub: Sage Publications Inc. place: Thousand Oaks, California artinfo: ui: 192230560 192230560 192230560 10.1177/27536351251391632 192230560 ppf: 1 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Medication Adherence and Its Determinants Among Adults With Heart Failure: A Study in Selected Hospitals of North Shewa Zone, Oromia, Ethiopia (2024)—A Multicenter Institutional-Based Cross-Sectional Study. aug: au: Mohammed, Abdurehman Seid Kemal, Wubanchi Seid Kolbay, Ali Seid Yesuf, Mustofa Hassen Abebe, Selam Seyoum Solomon, Bisrat Deress, Getachew Mekete affil: Department of Public Health, Kidus Petros Specialized Hospital, Addis Ababa, Ethiopia sug: subj: Heart Failure Drug Therapy Medication Compliance Evaluation Hospitals, Rural Ethiopia Ethiopia Human Multicenter Studies Cross Sectional Studies Simple Random Sample Descriptive Statistics Data Analysis Software Scales Logistic Regression Health Knowledge Evaluation Odds Ratio Confidence Intervals Health Services Accessibility Interviews Structured Questionnaires Record Review Coefficient alpha Goodness of Fit Chi Square Test Multiple Logistic Regression Models, Statistical Comorbidity Drugs, Prescription Supply and Distribution Health Expenditures Medication Compliance Education Multivariate Analysis Adolescence Adult Middle Age Aged Male Female Adolescent: 13-18 years Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Background: Effective management of heart failure (HF) critically relies on adherence to evidence-based pharmacotherapy. However, adherence remains suboptimal, contributing to preventable hospital readmissions, disease progression, and increased healthcare costs. This study assessed medication adherence and associated factors among adult HF patients in selected hospitals of North Shewa Zone, Oromia, Ethiopia. Methods: An institutional-based cross-sectional study was conducted among 327 adult HF patients selected via simple random sampling. The sample size was calculated using a single population proportion formula (P =.738, 95% confidence interval [CI], 5% margin of error) and adjusted for a 10% non-response rate. Medication adherence was measured using the Amharic version of the Morisky Medication Adherence Scale (MMAS-8). Data were entered and analyzed using SPSS version 26. Logistic regression identified factors associated with adherence, with statistical significance set at P <.05. Results: Out of 327 participants, 165 (50.5%) were female, with a mean age of 43 ± 17.6 years. Good medication adherence was observed in 146 participants (44.65%). Independent predictors of adherence included higher HF knowledge (AOR = 2.03; 95% CI = 1.13-3.66; P =.018), access to free medications (AOR = 1.78; 95% CI = 1.04-3.03; P =.034), and receiving education on medication adherence (AOR = 2.20; 95% CI = 1.22-3.97; P =.009). Conclusion and Recommendations: Less than half of HF patients demonstrated good medication adherence. Structured patient education, reliable access to medications, and improved HF knowledge were key determinants of adherence. Interventions targeting these factors are strongly recommended to enhance medication adherence and improve clinical outcomes among HF patients in North Shewa Zone. pubtype: Academic Journal doctype: equations & formulas research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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