Dietary factors in Helicobacter pylori infection control: A review of in vitro and in vivo data, including case-controls.
Helicobacter pylori poses a major threat to human health, primarily due to its tumorigenic potential and ability to cause tissue damage. Because of its strong association with gastric cancer and mucosa-associated lymphoid tissue lymphoma, H. pylori is classified as a class I carcinogen. Its eradicat...
| Published in: | Nutrition & Health Vol. 32; no. 1; pp. 71 - 81 |
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| Main Authors: | , , , |
| Format: | review tables/charts Journal Article |
| Published: |
Sage Publications Inc.
Jan2026
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=192252416&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 192252416 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 02601060 NTH jtl: Nutrition & Health issn: 02601060 maglogo: Y pubinfo: dt: Jan2026 vid: 32 iid: 1 pid: 344 pub: Sage Publications Inc. place: Thousand Oaks, California artinfo: ui: 192252416 187441674 192252416 192252416 10.1177/02601060251366000 192252416 ppf: 71 ppct: 10 formats: tig: atl: Dietary factors in Helicobacter pylori infection control: A review of in vitro and in vivo data, including case-controls. aug: au: Boyanova, Liliya Yordanova Markovska, Rumyana Donkova Gergova, Raina Tsvetanova Boyanova, Lyudmila affil: Department of Medical Microbiology, Medical University of Sofia, Sofia, Bulgaria sug: subj: Helicobacter Infections Drug Therapy Helicobacter Infections Prevention and Control Drug Interactions Helicobacter Infections Complications Drug Resistance, Microbial Cranberry Therapeutic Use Green Tea Therapeutic Use Prebiotics Therapeutic Use Plants, Medicinal Therapeutic Use Algae Honey Therapeutic Use Curcumin Therapeutic Use Propolis Therapeutic Use NF-kappa B Drug Effects Signal Transduction Drug Effects Cox-2 Inhibitors Therapeutic Use Broccoli Therapeutic Use Dietary Supplements Therapeutic Use Patient Safety Drug Efficacy Antiinflammatory Agents Therapeutic Use Antibiotics Therapeutic Use Ulcer Drug Therapy Urease Antagonists and Inhibitors Antineoplastic Agents Therapeutic Use ab: Helicobacter pylori poses a major threat to human health, primarily due to its tumorigenic potential and ability to cause tissue damage. Because of its strong association with gastric cancer and mucosa-associated lymphoid tissue lymphoma, H. pylori is classified as a class I carcinogen. Its eradication has become a challenge due to increasing antibiotic resistance rates. This implies the need to investigate nutritional factors for their anti- H. pylori effects. This study aimed to encompass data regarding anti-inflammatory, antibacterial, anti-adhesive, anti-ulcer, anti-urease and anti-cancer properties of seven non-antibiotic agents against H. pylori. We assessed articles in English using Science Direct, Scopus and Google Scholar, focusing mostly on recent publications. There are data pointing to the strong anti-adhesive action of cranberry, green tea and Arthrospira (Spirulina) spp. The anti-ulcer effect of green tea, Nigella sativa and microalgae was demonstrated in rat models. Cranberry, microalgae, honey and curcumin inhibit the urease activity of H. pylori. Propolis, green tea and curcumin interfere with the nuclear factor kappa B signalling pathway, while the last two as well as Arthrospira spp. inhibit cyclooxygenase-2. There are in vivo clinical trials indicating that cranberry, Nigella sativa, broccoli and curcumin can improve the success of eradication regimens, while honey showed a preventive effect. Additional trials are needed to determine the precise dose regimens and whether the natural or encapsulated product is more effective. Potential side effects and drug–drug interactions should be taken into account. pubtype: Academic Journal doctype: review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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