Acute‐Phase Response Following Different Modalities of Non‐Surgical Periodontal Treatment in Subjects Affected by Periodontitis and Co‐Morbid Hypertension: A Randomised Clinical Trial.
Aim: To compare acute‐phase response and blood pressure levels following full‐mouth or quadrant non‐surgical periodontal treatment (FM‐SRP or Q‐SRP) in patients affected by hypertension and periodontitis. Patients and Methods: Forty patients affected by hypertension and periodontitis were enrolled a...
| Publicado en: | Journal of Clinical Periodontology Vol. 53; no. 3; pp. 350 - 362 |
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| Autores principales: | , , , , , , |
| Formato: | research tables/charts randomized controlled trial Journal Article |
| Publicado: |
Wiley-Blackwell
Mar2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=192268354&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 192268354 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03036979 8E3 jtl: Journal of Clinical Periodontology issn: 03036979 maglogo: Y pubinfo: dt: Mar2026 vid: 53 iid: 3 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 192268354 189700536 192268354 192268354 10.1111/jcpe.70068 192268354 ppf: 350 ppct: 12 formats: tig: atl: Acute‐Phase Response Following Different Modalities of Non‐Surgical Periodontal Treatment in Subjects Affected by Periodontitis and Co‐Morbid Hypertension: A Randomised Clinical Trial. aug: au: Petrini, Morena Gennai, Stefano Marruganti, Crystal Marhl, Urska Izzetti, Rossana Nisi, Marco Graziani, Filippo affil: Department of Medical, Oral and Biotechnological Science, University of Chieti, Chieti, Italy sug: subj: Inflammation Comorbidity Hypertension Complications Chronic Periodontitis Complications Dental Scaling Methods Periodontitis Therapy Treatment Outcomes Blood Pressure Physiology Human Male Female Middle Age Aged Randomized Controlled Trials Random Assignment C-Reactive Protein Blood Periodontics Root Planing Vital Signs Comparative Studies Multiple Regression Hypertension Drug Therapy Italy Academic Medical Centers Biological Markers Blood Interleukins Blood Questionnaires Quality of Life Dental Instruments Mann-Whitney U Test Analysis of Variance Post Hoc Analysis Kruskal-Wallis Test Multiple Linear Regression Funding Source Descriptive Statistics Data Analysis Software T-Tests Age Factors Sex Factors Smoking Complications Glycated Hemoglobin Blood Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Aim: To compare acute‐phase response and blood pressure levels following full‐mouth or quadrant non‐surgical periodontal treatment (FM‐SRP or Q‐SRP) in patients affected by hypertension and periodontitis. Patients and Methods: Forty patients affected by hypertension and periodontitis were enrolled and randomly allocated to either the FM‐SRP or Q‐SRP group. Periodontal parameters were registered at baseline and 3 months after treatment. Blood samples and vital signs were collected at baseline, 24 h and 3 months after treatment. Primary outcomes were high‐sensitivity C‐reactive protein (hs‐CRP) concentration 24 h post operation and the variation in levels of blood pressure (BP). Results: Significant increase in hs‐CRP levels was observed at 24 h, with FM‐SRP presenting higher values than Q‐SRP (p < 0.05). In terms of periodontal outcomes, both treatment regimens proved equally effective. Systolic BP was significantly reduced at days 1 and 90 in both groups (p < 0.01), while a 90‐day significant decrease in diastolic BP was detected only in the Q‐SRP group (p < 0.01). Multiple regression analysis suggests that the peak of hs‐CRP at 24 h may influence BP reduction at Day 90. Conclusions: Q‐SRP may be preferred in patients affected by hypertension and periodontitis, as a higher post‐operative inflammatory response was associated with lower improvements in BP control in the medium term. pubtype: Academic Journal doctype: research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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