Alcohol approach–avoidance task behavior and brain potentials differentially predict ecologically assessed alcohol craving and consumption in early emerging adulthood.

Aims: The current study measured the extent to which different neurobehavioral indices of incentive‐motivational salience attribution to alcohol cues predict alcohol craving and consumption in the natural environment. Design, setting, and participants: Laboratory study at a university in Missouri, U...

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Publicado en:Addiction Vol. 121; no. 4; pp. 804 - 825
Autores principales: Cofresí, Roberto U., Keerstock, Sandie, Kohen, Casey B., Piasecki, Thomas M., Bartholow, Bruce D.
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Apr2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2026
      vid: 121
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/add.70247
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        atl: Alcohol approach–avoidance task behavior and brain potentials differentially predict ecologically assessed alcohol craving and consumption in early emerging adulthood.
      aug:
        au:
          Cofresí, Roberto U.
          Keerstock, Sandie
          Kohen, Casey B.
          Piasecki, Thomas M.
          Bartholow, Bruce D.
        affil: Department of Psychological Sciences, University of Missouri – Columbia, Columbia MO,, USA
      sug:
        subj:
          Alcohol Drinking Evaluation
          Avoidance (Psychology)
          Health Behavior Evaluation
          Brain Physiology
          Craving Evaluation
          Motivation
          Natural Environment
          Psychological Tests
          Cues
          Attention
          Human
          Young Adult
          Funding Source
          Missouri
          Smartphone
          Male
          Female
          Task Performance and Analysis
          Electroencephalography
          Reaction Time
          Conflict (Psychology)
          Neurosciences
          Positive Psychology
          Evoked Potentials
          Descriptive Statistics
          Male
          Female
      ab: Aims: The current study measured the extent to which different neurobehavioral indices of incentive‐motivational salience attribution to alcohol cues predict alcohol craving and consumption in the natural environment. Design, setting, and participants: Laboratory study at a university in Missouri, USA, followed by a smartphone‐based 21‐day ecological momentary assessment (EMA) protocol. Participants were emerging adults (N = 218–268 [52–56% female], age 18–20). Measurements: Participants completed an alcohol cue approach‐avoidance task while their electroencephalogram (EEG) was recorded. Behavioral measures (response time) indexed the strength of cue‐activated approach vs. avoidance tendency. Cue‐locked event‐related potentials provided EEG‐based neural measures of motivated attention (P3 amplitude) and approach‐avoidance conflict (N450 amplitude). From EMA, measures of alcohol consumption dynamics (as indexed by estimated blood alcohol concentration [eBAC], g/dL) during real‐world drinking episodes were obtained, as were measures of alcohol craving (7‐point visual analogue scale) dynamics during and outside these episodes. Findings Different approach‐avoidance task‐derived behavioral and neural measures rank‐ordered participants differently. Participants who approached alcohol cues more rapidly in lab subsequently showed steeper increases in craving (∆B ± standard error [SE] = 1.042 ± 0.499 point/hr), and eBAC (∆B ± SE = 0.046 ± 0.017 g/dl/hr), during real‐world drinking episodes. Participants who avoided alcohol cues more slowly in lab also showed steeper increases in eBAC (∆B ± SE = 0.056 ± 0.017 g/dl/hr). Participants with larger P3 during alcohol cue approach in lab subsequently showed steeper increases in eBAC (∆B ± SE = 0.048 ± 0.017 g/dl/hr), as did those with smaller P3 during alcohol cue avoidance (∆B ± SE = 0.025 ± 0.017 g/dl/hr). Participants with smaller N450 during alcohol cue approach in lab subsequently showed steeper increases in craving during drinking episodes (∆B ± SE = 1.465 ± 0.607 point/hr). Tests examining lab‐based neurobehavioral measures as predictors of craving dynamics during nondrinking moments, such as following incidental cue exposure, generally were inconclusive. Conclusions: Incentive salience toward alcohol may influence alcohol seeking (including craving) and alcohol consumption through distinct behavioral risk pathways in different people.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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