Neural Processing of Speech Sounds in Autistic Kindergarteners as a Predictor of Reading Outcomes.
Phonology is an important foundation of reading development; however, little is known about the neural substrates of speech sound processing and reading development in autistic children. We investigated early auditory event-related potentials (ERPs) in response to speech sounds and their association...
| Publicado en: | Journal of Autism & Developmental Disorders Vol. 56; no. 4; pp. 1418 - 1436 |
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| Autores principales: | , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Apr2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=192345538&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 192345538 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01623257 AUT jtl: Journal of Autism & Developmental Disorders issn: 01623257 maglogo: N pubinfo: dt: Apr2026 vid: 56 iid: 4 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 192345538 181015923 192345538 192345538 10.1007/s10803-024-06638-2 192345538 ppf: 1418 ppct: 18 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Neural Processing of Speech Sounds in Autistic Kindergarteners as a Predictor of Reading Outcomes. aug: au: Manning, Brittany L. Hosseini, Kianoosh Yang, Eunjin Buzzell, George A. Landi, Nicole Kim, So Hyun affil: https://ror.org/000e0be47 Department of Medical Social Sciences and Institute for Innovations in Developmental Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA sug: subj: Phonetics Autism Spectrum Disorder Physiopathology Reading Speech Perception Evoked Potentials, Auditory Language Development Human Prospective Studies Readability Case Control Studies Acoustic Stimulation Child, Preschool Child Male Female Regression Intelligence Funding Source Scales Electroencephalography Descriptive Statistics Data Analysis Software Child, Preschool: 2-5 years Child: 6-12 years Male Female ab: Phonology is an important foundation of reading development; however, little is known about the neural substrates of speech sound processing and reading development in autistic children. We investigated early auditory event-related potentials (ERPs) in response to speech sounds and their association with reading ability (word recognition and reading comprehension). 56 kindergarteners (28 ASD, 28 TD) completed an ERP task using rhyming, bisyllabic pseudowords (/gibu/ and /bidu/) in an old/new design: 50% "old" and 50% "new" stimuli presented following a sensitization block of 100% "old" stimuli. Behavioral measures of reading ability were completed at kindergarten entry and exit. Results from generalized linear mixed models revealed a significant three-way interaction between stimuli ("new" vs. "old"), diagnosis (ASD vs. TD), and reading ability (for word recognition and reading comprehension) for P1 and P2 amplitude. Follow-up analyses revealed that autistic children with lower reading abilities showed greater P1 and P2 amplitudes for "new" vs. "old" stimuli, with effects ranging from marginal to significant (p's 0.04–0.07). Regression analyses revealed that old/new ERP difference scores significantly predicted later word recognition at kindergarten year-end (P1 amplitude: p =.05; P2 amplitude: p =.04), but not reading comprehension, controlling for sex and nonverbal IQ. Autistic children with poorer reading skills, specifically those with weaker word recognition abilities, show neural differences when processing speech sounds compared to autistic peers with greater reading ability and typically developing children. A better understanding of the neural basis of speech sound processing could enhance our insight into the heterogeneity in reading among individuals with ASD and guide future treatment approaches. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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