Comparison of the Risk of Early Postoperative Infection and Length of Hospital Stay between Sarcopenic and Nonsarcopenic Adults Undergoing Live Donor Liver Transplantation Using Computed Tomography.

Objectives: Computed tomography (CT)-based sarcopenia assessment and the risk of early postoperative infection among adults undergoing live donor liver transplantation. This article also compares the postoperative length of hospital stay in sarcopenic and nonsarcopenic patients after live donor live...

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Published in:Indian Journal of Radiology & Imaging Vol. 36; no. 2; pp. 210 - 216
Main Authors: Yadav, Garima, Ganesan, Prem Kumar, Khadaria, Narottam, Chaudhary, Abhideep, Raj, Shashank
Format: diagnostic images research tables/charts Journal Article
Published: Thieme Medical & Scientific Publishers Private Limited Apr2026
Online Access:View this record in EBSCOhost
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      jtl: Indian Journal of Radiology & Imaging
      issn: 09713026
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      dt: Apr2026
      vid: 36
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      pub: Thieme Medical & Scientific Publishers Private Limited
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        10.1055/s-0045-1809625
        192375880
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        atl: Comparison of the Risk of Early Postoperative Infection and Length of Hospital Stay between Sarcopenic and Nonsarcopenic Adults Undergoing Live Donor Liver Transplantation Using Computed Tomography.
      aug:
        au:
          Yadav, Garima
          Ganesan, Prem Kumar
          Khadaria, Narottam
          Chaudhary, Abhideep
          Raj, Shashank
        affil: Department of Radiology and Imaging, BLK Super Speciality Hospital, New Delhi, India
      sug:
        subj:
          Surgical Wound Infection Risk Factors
          Length of Stay
          Sarcopenia Radiography
          Tomography, X-Ray Computed
          Living Donors
          Liver Transplantation
          Risk Assessment
          India
          Human
          Transplant Recipients
          Radiography, Abdominal
          Lumbar Vertebrae Radiography
          Muscle, Skeletal Radiography
          Image Processing, Computer Assisted
          Algorithms
          Abdominal Muscles Radiography
          Postoperative Care
          Blood Culture
          Microbial Culture and Sensitivity Tests
          Comparative Studies
          Psoas Muscles Radiography
          Erector Spinae Muscles Radiography
          Quadratus Lumborum Muscles Radiography
          Rectus Abdominis Muscles Radiography
          Descriptive Statistics
          Unpaired T-Tests
          Fisher's Exact Test
          Chi Square Test
          Data Analysis Software
          Male
          Female
          Adult
          Middle Age
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Objectives: Computed tomography (CT)-based sarcopenia assessment and the risk of early postoperative infection among adults undergoing live donor liver transplantation. This article also compares the postoperative length of hospital stay in sarcopenic and nonsarcopenic patients after live donor liver transplantation. Materials and Methods: Sixty live donor liver transplantation recipients undergoing abdominal CT scans were included during the period from April 2022 to February 2024. CT data was obtained via 128-slice Revolution Frontier CT by GE Healthcare. Individual vertebral levels were identified on CT scan and skeletal muscle cross-sectional areas were computed using MATLAB algorithms. SliceOmatic software aided in muscle area determination and L3 vertebra served as the reference for assessing abdominal muscles. Skeletal muscle index was derived by normalizing muscle area to height. Sex-specific sarcopenia cutoffs were applied based on CT findings. Postoperative care included surveillance for infections using blood culture positivity. Results: Note that 76.47% of the infected patients were sarcopenic while 23.53% were nonsarcopenic. Also, 32.56% of the noninfected patients were sarcopenic whereas 67.44% were nonsarcopenic (p -value = 0.003). Postop length of hospital stay in days showed a significant difference between the two groups (p ≤ 0.001), with the sarcopenic group having the greatest median postop length of hospital stay. Conclusion: Pretransplant sarcopenia as determined by skeletal muscle index is associated with an increased risk of posttransplant infections in a group of patients undergoing liver transplantation as well as longer stay in hospital.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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