Particulate Evacuation Under NPWT: Bench Evaluation of a Multilayer Foam Prototype Versus Commercial Dressings in a Simulated Exudate Model.

Negative pressure wound therapy (NPWT) is widely used to facilitate healing by improving local perfusion, reducing edema and controlling exudate. The porous foam dressing is central to NPWT effectiveness, however, its performance in viscous, particle‐rich exudates remains challenging. Standard indus...

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Published in:International Wound Journal Vol. 23; no. 3; pp. 1 - 9
Main Authors: Zorrilla de la Fuente, Patricia, Castillo, Federico, Diban, Nazely, Lázaro‐Martínez, José Luis, Quevedo Revilla, Fernando, García Ruiz, Gerardo, Sancibrian, Ramón, Peralta, Galo
Format: pictorial research tables/charts Journal Article
Published: Wiley-Blackwell Mar2026
Online Access:View this record in EBSCOhost
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      dt: Mar2026
      vid: 23
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/iwj.70872
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        atl: Particulate Evacuation Under NPWT: Bench Evaluation of a Multilayer Foam Prototype Versus Commercial Dressings in a Simulated Exudate Model.
      aug:
        au:
          Zorrilla de la Fuente, Patricia
          Castillo, Federico
          Diban, Nazely
          Lázaro‐Martínez, José Luis
          Quevedo Revilla, Fernando
          García Ruiz, Gerardo
          Sancibrian, Ramón
          Peralta, Galo
        affil: Instituto de Investigación Sanitaria Valdecilla (IDIVAL), Santander, Spain
      sug:
        subj:
          Simulations
          Exudates and Transudates
          Negative Pressure Wound Therapy
          Wound Healing
          Equipment Design
          Bandages and Dressings
          Foam Dressings
          Product Evaluation
          In Vitro Studies
          Comparative Studies
          Wound Care Methods
          Descriptive Statistics
          Wound Infection Prevention and Control
          Funding Source
      ab: Negative pressure wound therapy (NPWT) is widely used to facilitate healing by improving local perfusion, reducing edema and controlling exudate. The porous foam dressing is central to NPWT effectiveness, however, its performance in viscous, particle‐rich exudates remains challenging. Standard industry tests often rely on protein‐free aqueous solutions, which overlook the complex rheology and particulate load of real wounds. This study reports a bench evaluation of a multilayer foam prototype compared with three commercial dressings under NPWT, using a simulated viscous exudate with suspended particles. We recorded 60‐min drainage curves and quantified effluent turbidity as a simple, interpretable proxy for particulate transport, summarised as percentage of input turbidity recovered. The mass‐based endpoint (percent solid matter recovered) showed the same ranking as turbidity. At −75 mmHg, the prototype recovered 31.6% of input turbidity, exceeding commercial foams (≤ 9.7%). At −125 mmHg, particulate recovery decreased across all dressings (≤ 9.1%). A matrix‐only control indicated that commercial effluents, particularly at −75 mmHg, clustered near background level, whereas the prototype evacuated substantially more particulate while maintaining robust fluid drainage. These findings suggest that moderate negative pressure and multilayer architecture can help preserve channel patency and reduce clogging in complex exudates. We highlight the need for test methodologies that incorporate viscosity and particulate content, and for practical guidance that links dressing architecture and pressure settings to exudate characteristics. Prospective validation, including larger‐sample confirmation, particle‐size distributions and ultimately clinical endpoints, is warranted. Summary: Clinical selection of NPWT pressure and dressing should reflect exudate properties, and industrial standards should measure viscosity and particulate load instead of using protein‐free aqueous surrogates to ensure accurate, clinically relevant testing.This study evaluates a multilayer foam prototype against three commercial dressings under NPWT, using an innovative simulated viscous exudate with suspended particles to characterise drainage behaviour via time‐volume curves and a simple, interpretable endpoint (percent of input turbidity recovered; confirmed by percent solid matter recovered).Findings show that particulate evacuation depends on pressure and dressing architecture: at −75 mmHg the prototype evacuates substantially more particulate (31.6%) than commercial foams (≤ 9.7%), whereas at −125 mmHg particulate recovery decreases across all dressings (≤ 9.1%), consistent with compression‐induced pore narrowing and filter‐cake formation that limit particle transport.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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