Home-based extended rehabilitation for older people with frailty (HERO): a randomised controlled trial.
Objective To evaluate whether home-based extended rehabilitation for older people with frailty after hospitalisation with an acute illness or injury can improve physical health-related quality of life. Trial design Multi-centre, individually randomised controlled parallel group superiority trial. Se...
| Publicado en: | Age & Ageing Vol. 55; no. 2; pp. 1 - 14 |
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| Autores principales: | , , , , , , , , , |
| Formato: | Artículo |
| Publicado: |
Oxford University Press / USA
Feb2026
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=192513140&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 192513140 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 00020729 AGA jtl: Age & Ageing issn: 00020729 maglogo: N pubinfo: dt: Feb2026 vid: 55 iid: 2 pid: 622 pub: Oxford University Press / USA artinfo: ui: 192513140 10.1093/ageing/afag011 ppf: 1 ppct: 13 formats: tig: atl: Home-based extended rehabilitation for older people with frailty (HERO): a randomised controlled trial. aug: au: Clegg, Andrew Prescott, Matthew Collinson, Michelle Goodwin, Victoria A Thompson, Ellen Bestwick, Rebecca Bojke, Chris Clarke, David Day, Florence Forster, Anne affil: Academic Unit for Ageing & Stroke Research, Leeds Institute of Health Sciences, University of Leeds, Leeds, LS2 9JT, UKBradford Teaching Hospitals NHS Foundation Trust, Bradford Institute for Health Research, Bradford, BD9 6RJ, UK Academic Unit for Ageing & Stroke Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, BD9 6RJ, UK Clinical Trials Research Unit (CTRU), Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, LS2 9JT, UK Faculty of Health and Life Sciences, University of Exeter, Exeter, EX2 4SG, UK Academic Unit of Health Economics, Leeds Institute of Health Sciences, University of Leeds, Leeds, LS2 9JT, UK Academic Unit for Ageing & Stroke Research, Leeds Institute of Health Sciences, University of Leeds, Leeds, LS2 9JT, UK su: England Home care services Self-evaluation Health status indicators Cost effectiveness Clinical trials Randomized controlled trials Geriatric rehabilitation Quality of life Hospital care of older people Old age Mortality risk factors Physical therapy Wounds & injuries Risk assessment Acute diseases Research funding Frail elderly Long-term health care Statistical sampling Exercise therapy Patient readmissions Logistic regression analysis Treatment effectiveness Treatment duration Discharge planning Severity of illness index Descriptive statistics Health surveys Odds ratio Research Confidence intervals Barthel Index Data analysis software Proportional hazards models sug: subj: Home care services Self-evaluation Health status indicators Cost effectiveness Clinical trials Randomized controlled trials Geriatric rehabilitation Quality of life Hospital care of older people Old age England Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology) Services for the Elderly and Persons with Disabilities Home Health Care Services Offices of all other health practitioners Offices of All Other Miscellaneous Health Practitioners Marketing Research and Public Opinion Polling Mortality risk factors Physical therapy Wounds & injuries Risk assessment Acute diseases Research funding Frail elderly Long-term health care Statistical sampling Exercise therapy Patient readmissions Logistic regression analysis Treatment effectiveness Treatment duration Discharge planning Severity of illness index Descriptive statistics Health surveys Odds ratio Research Confidence intervals Barthel Index Data analysis software Proportional hazards models keyword: arm copyrightHolder:British Geriatrics Society copyrightYear:2026 exercise frailty hospitalization https://dx.doi.org/10.1093/ageing/afag011 inLanguage:en national health service (uk) older adult older people publisher:Oxford University Press randomization RCT rehabilitation sameAs:https://pubmed.ncbi.nlm.nih.gov/41719425/ trial arm copyrightHolder:British Geriatrics Society copyrightYear:2026 exercise frailty hospitalization https://dx.doi.org/10.1093/ageing/afag011 inLanguage:en national health service (uk) older adult older people publisher:Oxford University Press randomization RCT rehabilitation sameAs:https://pubmed.ncbi.nlm.nih.gov/41719425/ trial ab: Objective To evaluate whether home-based extended rehabilitation for older people with frailty after hospitalisation with an acute illness or injury can improve physical health-related quality of life. Trial design Multi-centre, individually randomised controlled parallel group superiority trial. Setting Recruitment from 15 NHS Trusts in England, with home-based intervention delivery. Participants Eligible participants were 65 years or older with mild/moderate/severe frailty (5–7 on Clinical Frailty Scale) admitted to hospital with acute illness/injury, then discharged home. Interventions Participants were randomly assigned (1.28:1) to the Home-based Older People's Exercise (HOPE) programme—a 24-week home-based manualised, progressive exercise intervention as extended rehabilitation, or usual care (control). Main outcome measures Primary outcome was physical health-related quality of life, measured using the physical component summary (PCS) of the modified Short Form 36-item health questionnaire (SF36) at 12 months. Secondary outcomes at six and 12 months included functional independence, death, hospitalisations and care home admissions. Results We randomised 740 participants (410 HOPE, 330 control). Intention-to-treat analyses showed no evidence that HOPE was superior to control for 12-month PCS score (adjusted mean difference −0.22, 95% CI -1.47 to 1.03; P = .73). There was some evidence of a higher rate of all-cause hospitalisations in the control arm (incidence rate ratio 1.12, 95% CI 1.00 to 1.25; P = .05). The intervention was not cost-effective. Conclusions We do not recommend routine commissioning of extended rehabilitation for older people with frailty after discharge home from hospital or intermediate care, following an acute admission with a medical illness or injury. Trial registration ISRCTN-13927531 (19/04/2017). pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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