Antihypertensive medication adherence and associated factors in older adults requiring long-term care: the LIFE Study.
Background Consistent antihypertensive treatment reduces cardiovascular risk, but older adults requiring long-term care (LTC) due to functional impairment may have a diminished ability to adhere to treatment. Objective To examine antihypertensive medication adherence among older adults requiring LTC...
| Publicado en: | Age & Ageing Vol. 55; no. 2; pp. 1 - 12 |
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| Autores principales: | , , , , |
| Formato: | Artículo |
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Oxford University Press / USA
Feb2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=192513146&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 192513146 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 00020729 AGA jtl: Age & Ageing issn: 00020729 maglogo: N pubinfo: dt: Feb2026 vid: 55 iid: 2 pid: 622 pub: Oxford University Press / USA artinfo: ui: 192513146 10.1093/ageing/afag018 ppf: 1 ppct: 11 formats: tig: atl: Antihypertensive medication adherence and associated factors in older adults requiring long-term care: the LIFE Study. aug: au: Sagara, Kumi Goto, Kenichi Maeda, Megumi Oda, Futoshi Fukuda, Haruhisa affil: Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan Department of Health Care Administration and Management, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan su: Japan Patient compliance Hypertension Retrospective studies Metropolitan areas Drugs Activities of daily living Old age Hypertension epidemiology Hypertension risk factors Risk assessment Research funding Vision disorders Health insurance reimbursement Long-term health care Logistic regression analysis Antihypertensive agents Functional status Cardiovascular diseases risk factors Descriptive statistics Multivariate analysis Longitudinal method Odds ratio Medical records Acquisition of data Medication therapy management Cognition disorders Geriatric assessment Medical care for older people Deglutition Hearing disorders Comparative studies Confidence intervals Data analysis software Paralysis Health care teams sug: subj: Patient compliance Hypertension Retrospective studies Metropolitan areas Drugs Activities of daily living Old age Japan Drugs and Druggists' Sundries Merchant Wholesalers Pharmaceutical and medicine manufacturing Pharmaceuticals and pharmacy supplies merchant wholesalers Hypertension epidemiology Hypertension risk factors Risk assessment Research funding Vision disorders Health insurance reimbursement Long-term health care Logistic regression analysis Antihypertensive agents Functional status Cardiovascular diseases risk factors Descriptive statistics Multivariate analysis Longitudinal method Odds ratio Medical records Acquisition of data Medication therapy management Cognition disorders Geriatric assessment Medical care for older people Deglutition Hearing disorders Comparative studies Confidence intervals Data analysis software Paralysis Health care teams keyword: antihypertensive agents cognitive ability cognitive function copyrightHolder:British Geriatrics Society copyrightYear:2026 deglutition functional impairment https://dx.doi.org/10.1093/ageing/afag018 hypertension inLanguage:en long-term care medication adherence mental processes older adult older adults paralysis publisher:Oxford University Press sameAs:https://pubmed.ncbi.nlm.nih.gov/41649297/ antihypertensive agents cognitive ability cognitive function copyrightHolder:British Geriatrics Society copyrightYear:2026 deglutition functional impairment https://dx.doi.org/10.1093/ageing/afag018 hypertension inLanguage:en long-term care medication adherence mental processes older adult older adults paralysis publisher:Oxford University Press sameAs:https://pubmed.ncbi.nlm.nih.gov/41649297/ ab: Background Consistent antihypertensive treatment reduces cardiovascular risk, but older adults requiring long-term care (LTC) due to functional impairment may have a diminished ability to adhere to treatment. Objective To examine antihypertensive medication adherence among older adults requiring LTC in Japan and to identify its associated factors. Design Retrospective cohort study. Setting 11 municipalities. Participants Individuals aged ≥65 years requiring LTC and diagnosed with hypertension between April 2016 and March 2020. Methods Medical claims data, LTC claims data and LTC certification data were analysed. The study outcome was antihypertensive medication adherence (proportion of days covered >0.8) over 1 year. Using logistic regression analysis, we assessed the associations between adherence and the following factors: care needs levels, paralysis, visual function, hearing function, swallowing function, cognitive function and need for medication intake assistance. Results The study cohort comprised 69 200 participants (nonadherent: 17 523; 25.3%). At LTC certification application, most participants lived at home (78.3% adherent vs. 64.1% nonadherent). Adherence was negatively associated with high care needs levels (odds ratio: 0.241, 95% confidence interval: 0.222–0.263), bilateral upper limb paralysis (0.605, 0.565–0.648), bilateral lower limb paralysis (0.837, 0.803–0.873), left upper limb paralysis (0.820, 0.746–0.921), moderate visual impairment (0.738, 0.675–0.808), severe hearing impairment (0.683, 0.549–0.853), severe swallowing impairment (0.199, 0.169–0.234), severe cognitive impairment (0.652, 0.621–0.684) and need for full medication intake assistance (0.296, 0.279–0.315). Conclusions Over 25% of older adults requiring LTC were nonadherent to antihypertensive treatment. These findings may help to identify high-risk individuals who could benefit from targeted interventions to support medication management. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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