Methodological approaches to estimate physical resilience in older adults: a comparison across two clinical settings.
Introduction Various methodological approaches exist to estimate physical resilience in older adults (phenotype, expected recovery, adapted ageing), but their comparative performance remains unclear. This study evaluated their agreement and predictive performance across two clinical contexts. Method...
| Publicado en: | Age & Ageing Vol. 55; no. 2; pp. 1 - 8 |
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| Autores principales: | , , , , , , , |
| Formato: | Artículo |
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Oxford University Press / USA
Feb2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=192513153&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 192513153 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 00020729 AGA jtl: Age & Ageing issn: 00020729 maglogo: N pubinfo: dt: Feb2026 vid: 55 iid: 2 pid: 622 pub: Oxford University Press / USA artinfo: ui: 192513153 10.1093/ageing/afag025 ppf: 1 ppct: 7 formats: tig: atl: Methodological approaches to estimate physical resilience in older adults: a comparison across two clinical settings. aug: au: Duin, Jan J Smits, Rosalinde A L Krans, Tim Dekkers, Olaf M Trompet, Stella Groot, Bas de Mooijaart, Simon P van den Bos, Frederiek affil: Department of Internal Medicine, Section Gerontology and Geriatrics, Leiden University Medical Center, Leiden, South Holland, The NetherlandsCenter for Medicine for Older People, Leiden University Medical Center, Leiden, South Holland, The Netherlands Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, South Holland, The NetherlandsDepartment of Internal Medicine, Section of Endocrinology and Metabolic Disorders, Leiden University Medical Center, Leiden, South Holland, The NetherlandsDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Central Denmark Region, Denmark Department of Emergency Medicine, Radboud University Medical Center, Nijmegen, Gelderland, The NetherlandsDepartment of Clinical Medicine, Research Center for Emergency Medicine, Aarhus University Hospital, Aarhus, Central Denmark Region, Denmark su: Netherlands Patients Emergency medical services Psychological adaptation Activities of daily living Old age Psychological resilience Predictive tests Secondary analysis Receiver operating characteristic curves Frail elderly Treatment effectiveness Cancer patients Descriptive statistics Hospital emergency services Functional status Longitudinal method Cancer chemotherapy Geriatric assessment Research Statistics Body movement Comparative studies Data analysis software Confidence intervals Tumors sug: subj: Patients Emergency medical services Psychological adaptation Activities of daily living Old age Netherlands Municipal police services Emergency and Other Relief Services Psychological resilience Predictive tests Secondary analysis Receiver operating characteristic curves Frail elderly Treatment effectiveness Cancer patients Descriptive statistics Hospital emergency services Functional status Longitudinal method Cancer chemotherapy Geriatric assessment Research Statistics Body movement Comparative studies Data analysis software Confidence intervals Tumors keyword: activities of daily living aging copyrightHolder:British Geriatrics Society copyrightYear:2026 expected recovery follow-up geriatrics https://dx.doi.org/10.1093/ageing/afag025 inLanguage:en instrumental activities of daily living older adult older people phenotype physical function physical resilience psychological publisher:Oxford University Press residual resilience sameAs:https://pubmed.ncbi.nlm.nih.gov/41649295/ stressor activities of daily living aging copyrightHolder:British Geriatrics Society copyrightYear:2026 expected recovery follow-up geriatrics https://dx.doi.org/10.1093/ageing/afag025 inLanguage:en instrumental activities of daily living older adult older people phenotype physical function physical resilience psychological publisher:Oxford University Press residual resilience sameAs:https://pubmed.ncbi.nlm.nih.gov/41649295/ stressor ab: Introduction Various methodological approaches exist to estimate physical resilience in older adults (phenotype, expected recovery, adapted ageing), but their comparative performance remains unclear. This study evaluated their agreement and predictive performance across two clinical contexts. Methods We applied three methodological approaches in two cohorts: older adults receiving chemotherapy (TENT) and those presenting with acute illness at the emergency department (APOP). Physical functioning was assessed using Katz Activities of Daily Living and Lawton Instrumental Activities of Daily Living scales. The phenotype approach measured functional change after the health stressor; the expected recovery approach compared actual to predicted recovery based on clinical characteristics; and the adapted ageing approach assessed baseline function relative to expected levels given clinical risk profile. Outcomes at 12 months included mortality and a composite endpoint of functional decline, quality of life decline or mortality. Agreement was assessed using Cohen's kappa and predictive performance using area under the curve (AUC). Results The TENT cohort included 330 patients (median age 75 years; 43% female) and APOP included 2111 patients (median age 78 years; 54% female). Agreement between approaches was poor to moderate (κ = −0.10 to 0.64). All approaches showed only moderate discriminative ability for 12-month mortality (AUC 0.55–0.69) and composite outcomes (AUC 0.52–0.66). The physical resilience approaches provided limited added discrimination beyond simple predictors: functional score at follow-up (AUC 0.65–0.69) and age (AUC 0.48–0.67). Conclusion Various physical resilience approaches identified different patient groups as resilient and demonstrated limited prognostic value. Current approaches may inadequately capture the dynamic construct of physical resilience; higher-frequency longitudinal measures may better quantify physical resilience for clinical practice. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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