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Antimuscarinic medication used for the treatment of overactive bladder in women and the risk of cognitive decline, cardiovascular disease and mortality—a systematic review.

Background Overactive bladder is common among older women and often managed with antimuscarinic agents. These medications contribute to cumulative anticholinergic burden, which has been associated with adverse outcomes including cognitive decline, cardiovascular morbidity and mortality. This study a...

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Published in:Age & Ageing Vol. 55; no. 2; pp. 1 - 12
Main Authors: Maguire, Turlough, Marr, Calum, Barry, Heather, Abdel-Fattah, Mohamed, McGuinness, Bernadette
Format: Article
Published: Oxford University Press / USA Feb2026
Subjects:
Competency assessment (Law)
Psychology of women
Memory
Adults
Dementia risk factors
Cognition disorder risk factors
Mortality risk factors
Risk assessment
Medical information storage & retrieval systems
Cognitive testing
CINAHL database
Cardiovascular diseases risk factors
Meta-analysis
Descriptive statistics
Systematic reviews
Odds ratio
MEDLINE
Muscarinic antagonists
Confidence intervals
Data analysis software
Overactive bladder
Patient aftercare
Psychology information storage & retrieval systems
Online Access:View this record in EBSCOhost