Collaborative medication reviews during acute primary care admissions for older adults with polypharmacy: a randomised controlled trial.
Background Polypharmacy in older adults is associated with inappropriate prescribing and adverse drug events. In a previous trial, we demonstrated improved Health-Related Quality of Life (HRQoL) following medication reviews by geriatricians and general practitioners in home-dwelling older adults. Wh...
| Publicado en: | Age & Ageing Vol. 55; no. 2; pp. 1 - 7 |
|---|---|
| Autores principales: | , , , , , , , , |
| Formato: | Artículo |
| Publicado: |
Oxford University Press / USA
Feb2026
|
| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=192513157&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 192513157 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 00020729 AGA jtl: Age & Ageing issn: 00020729 maglogo: N pubinfo: dt: Feb2026 vid: 55 iid: 2 pid: 622 pub: Oxford University Press / USA artinfo: ui: 192513157 10.1093/ageing/afag029 ppf: 1 ppct: 6 formats: tig: atl: Collaborative medication reviews during acute primary care admissions for older adults with polypharmacy: a randomised controlled trial. aug: au: Santervas, Leonor Roa Skovlund, Eva Kristoffersen, Espen Saxhaug Ringstad, Ingrid Beate Fjeld, Katrine Gahre Hove, Lene Hystad Jensen, Janicke Liaaen Wyller, Torgeir Bruun Romskaug, Rita affil: Institute of Clinical Medicine, University of Oslo, Oslo, NorwayDepartment of Geriatric Medicine, Oslo University Hospital, Oslo, NorwayHealth Agency, City of Oslo Health Services, Oslo, Norway Department of Public Health and Nursing, Norwegian University of Science and Technology, Trondheim, Norway Department of General Practice, Institute of Health and Society, University of Oslo, Oslo, NorwayDepartment of Neurology, Akershus University Hospital, Lørenskog, Norway Department of Oral Surgery and Oral Medicine, University of Oslo, Oslo, Norway Department of Cariology and Gerodontology, University of Oslo, Oslo, Norway Institute of Clinical Medicine, University of Oslo, Oslo, NorwayDepartment of Geriatric Medicine, Oslo University Hospital, Oslo, Norway Department of Geriatric Medicine, Oslo University Hospital, Oslo, Norway su: Norway Interprofessional relations Patients Primary health care Hospital admission & discharge Blind experiment Patient care Randomized controlled trials Quality of life Hospital care of older people Critical care medicine Old age Research funding Statistical sampling Medication error prevention Polypharmacy Descriptive statistics Analysis of covariance Conceptual structures Data analysis software sug: subj: Interprofessional relations Patients Primary health care Hospital admission & discharge Blind experiment Patient care Randomized controlled trials Quality of life Hospital care of older people Critical care medicine Old age Norway Marketing Research and Public Opinion Polling Research funding Statistical sampling Medication error prevention Polypharmacy Descriptive statistics Analysis of covariance Conceptual structures Data analysis software keyword: copyrightHolder:British Geriatrics Society copyrightYear:2026 family general practitioner geriatrics health-related quality of life Health-Related Quality of Life (HRQoL) https://dx.doi.org/10.1093/ageing/afag029 inLanguage:en medication review norway older adult older people physicians polypharmacy primary health care publisher:Oxford University Press randomization sameAs:https://pubmed.ncbi.nlm.nih.gov/41719423/ copyrightHolder:British Geriatrics Society copyrightYear:2026 family general practitioner geriatrics health-related quality of life Health-Related Quality of Life (HRQoL) https://dx.doi.org/10.1093/ageing/afag029 inLanguage:en medication review norway older adult older people physicians polypharmacy primary health care publisher:Oxford University Press randomization sameAs:https://pubmed.ncbi.nlm.nih.gov/41719423/ ab: Background Polypharmacy in older adults is associated with inappropriate prescribing and adverse drug events. In a previous trial, we demonstrated improved Health-Related Quality of Life (HRQoL) following medication reviews by geriatricians and general practitioners in home-dwelling older adults. Whether similar benefits can be achieved during acute admissions in primary care remains unclear. Objective To assess the effect of collaborative medication reviews during acute admissions to a Municipal Inpatient Acute Care (MIPAC) unit. Methods In this single-blind, parallel-group, randomised controlled trial, patients ≥70 years using ≥6 regular medications admitted to a MIPAC unit in Oslo, Norway, were randomised 1:1 to receive either a structured medication review or usual care. The intervention involved assessment by MIPAC physicians specialised in general practice, geriatric supervision and discussion with the patient's general practitioner. The primary outcome was HRQoL measured with the 15D instrument at 16 weeks. Secondary outcomes included physical and cognitive function, oral health, healthcare utilisation and mortality. Results We included 137 participants (mean age 85 years, 69% women; 67 intervention, 70 control). At 16 weeks, there was no significant difference in 15D scores between groups (mean difference 0.009; 95% CI, −0.063 to 0.079; P = .8). The intervention group had more medication changes during admission, but differences diminished post-discharge. No differences were observed in secondary outcomes. Conclusion Collaborative medication reviews during acute primary care admissions did not improve HRQoL. The findings underscore the need for longitudinal, patient-centred strategies initiated in clinically stable phases. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
|---|