Fcγ-receptor-activation by circulating immune complexes in systemic autoimmune diseases and its reduction by CD19-CAR T cell therapy.

Objectives The role of autoantibody-producing B cells in connective tissue diseases (CTD) has recently been highlighted by the successful treatment with CD19-targeting CAR T cells. Detrimental effects of autoantibodies are linked to the formation of deposited IgG complexes and the activation of immu...

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Bibliographic Details
Published in:Rheumatology Vol. 65; no. 3; pp. 1 - 11
Main Authors: Freitag, Merle, Kolb, Philipp, Falcone, Valeria, Claus, Maren, Schröder, Pauline, Andreeva, Ivana, Rodon, Lea, Ewald, Meike, Deicher, Franca Sophie, Stütz, Ayla Nadja
Format: pictorial research tables/charts Journal Article
Published: Oxford University Press / USA Mar2026
Online Access:View this record in EBSCOhost