Sensor‐Based Assessment of Asymmetry in Upper Limb Bradykinesia Among Patients With Parkinson's Disease and Scans Without Evidence of Dopaminergic Deficit (SWEDD).
Background: Bilateral motor asymmetry is a hallmark feature of Parkinson's disease (PD). However, few studies have quantitatively examined this feature in patients with scans without evidence of dopaminergic deficit (SWEDD). This study aimed to investigate upper limb asymmetry in bradykinesia among...
| Publicado en: | Parkinson's Disease (20420080) Vol. 2026; pp. 1 - 9 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
4/1/2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=192690450&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 192690450 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 20908083 B6DS jtl: Parkinson's Disease (20420080) issn: 20908083 maglogo: N pubinfo: dt: 4/1/2026 vid: 2026 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 192690450 192690450 192690450 10.1155/padi/6400390 192690450 ppf: 1 ppct: 8 formats: tig: atl: Sensor‐Based Assessment of Asymmetry in Upper Limb Bradykinesia Among Patients With Parkinson's Disease and Scans Without Evidence of Dopaminergic Deficit (SWEDD). aug: au: Kwon, Do Young Ko, Junghyuk Kwon, Yuri Kim, Ji-Won Witt, Karsten affil: Department of Neurology,, Korea University College of Medicine,, Ansan-City, South Korea, korea.ac.kr sug: subj: Wearable Sensors Utilization Hypokinesia Upper Extremity Physiopathology Parkinson Disease Physiopathology Dopaminergic Imaging Funding Source Human Matched Case Control Comparative Studies Spearman's Rank Correlation Coefficient Rotation Forearm Physiology Task Performance and Analysis Neuropsychological Tests Male Female Middle Age Aged Parkinson Disease Diagnosis Positron-Emission Tomography Descriptive Statistics Data Analysis Software One-Way Analysis of Variance Two-Way Analysis of Variance Post Hoc Analysis Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Background: Bilateral motor asymmetry is a hallmark feature of Parkinson's disease (PD). However, few studies have quantitatively examined this feature in patients with scans without evidence of dopaminergic deficit (SWEDD). This study aimed to investigate upper limb asymmetry in bradykinesia among PD and SWEDD patients using gyro sensors, focusing on finger tapping and forearm rotation task. Methods: We recruited 23 early‐stage, drug‐naïve PD patients, 23 SWEDD patients, and 20 age‐matched healthy controls. We recorded gyro sensor signals during 15‐s finger tapping and forearm rotation tasks. Bilateral asymmetry indices were calculated and compared among groups. In addition, repeated measure analysis of variance (ANOVA) was used to examine the interaction of task and group, and Spearman correlation analysis was conducted with clinical motor scores. Results: No significant group differences were found during finger tapping. However, during forearm rotation, PD patients exhibited significantly greater asymmetry than SWEDD patients in several indices, including RMS angular velocity, peak angular displacement, peak power, and total power. Task × group interaction effects were significant only in forearm rotation, and asymmetry indices from forearm rotation showed significant correlations with clinical motor scores. Conclusions: Forearm rotation is a sensitive task for detecting motor asymmetry in PD and for differentiating PD from SWEDD. These results suggest that quantitative motor asymmetry indices using wearable sensors could aid clinicians in the identification of potential SWEDD. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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