Preoperative, Perioperative, and Pathological Characteristics of Sigmoid, Rectosigmoid, and Upper Rectal Adenocarcinomas: A Retrospective Cohort Study from the Turkish Colorectal Cancer Database.
Aim This retrospective cohort study used the Turkish Society of Colon and Rectal Surgery Colorectal Cancer Database to compare the preoperative clinical characteristics and 30-day postoperative outcomes of patients undergoing curative surgery for adenocarcinomas of the sigmoid colon, rectosigmoid ju...
| Publicado en: | Turkish Journal of Colorectal Disease Vol. 36; no. 1; pp. 1 - 9 |
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| Autores principales: | , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Galenos Yayinevi Tic. LTD. STI
Mar2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=192696457&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 192696457 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 25364898 KYKD jtl: Turkish Journal of Colorectal Disease issn: 25364898 maglogo: N pubinfo: dt: Mar2026 vid: 36 iid: 1 pid: 28155 pub: Galenos Yayinevi Tic. LTD. STI artinfo: ui: 192696457 192696457 192696457 10.4274/tjcd.galenos.2025.2025-6-8 192696457 ppf: 1 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Preoperative, Perioperative, and Pathological Characteristics of Sigmoid, Rectosigmoid, and Upper Rectal Adenocarcinomas: A Retrospective Cohort Study from the Turkish Colorectal Cancer Database. aug: au: Benlice, Çiğdem Moniri, Ariorad Ramoğlu, Nur Bağda, Makbule Ayşegül Baca, Bilgi Group, Turkish Colorectal Cancer Database Study affil: Acıbadem Altunizade Hospital, Clinic of General Surgery, İstanbul, Türkiye sug: subj: Sigmoid Neoplasms Surgery Rectal Neoplasms Surgery Adenocarcinoma Surgery Surgery, Operative Methods Disease Attributes Preoperative Period Perioperative Care Treatment Outcomes Human Male Female Middle Age Aged Descriptive Statistics Retrospective Design Record Review Prospective Studies Turkiye Chi Square Test Fisher's Exact Test T-Tests Mann-Whitney U Test Magnetic Resonance Imaging Neoadjuvant Therapy Positron Emission Tomography Computed Tomography Data Analysis Software Post Hoc Analysis Power Analysis Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Aim This retrospective cohort study used the Turkish Society of Colon and Rectal Surgery Colorectal Cancer Database to compare the preoperative clinical characteristics and 30-day postoperative outcomes of patients undergoing curative surgery for adenocarcinomas of the sigmoid colon, rectosigmoid junction, and upper rectum. Method Patients who underwent curative resection for non-metastatic adenocarcinoma of the sigmoid colon, rectosigmoid junction, or upper rectum between January 2017 and January 2025 were identified. Tumors ≥10 cm from the anal verge were classified as upper rectal cancers. The three anatomical groups were compared regarding clinical parameters, 30-day outcomes, and histopathology. Statistical comparisons were performed using the chi-squared or Fisher's exact tests for categorical variables and the t-test or Mann-Whitney U test for continuous variables. Results A total of 634 patients were analyzed [sigmoid: 274 (43.3%), rectosigmoid: 174 (27.4%), upper rectum: 186 (29.3%)]. Patients with sigmoid cancer were older (mean 64±12 years) with a higher proportion of women (42%) than those with rectosigmoid and upper rectum cancer (p-value <0.001). Magnetic resonance imaging use was significantly higher in upper rectal tumors (73%) than in rectosigmoid (11%) and sigmoid (0%) tumors. Neoadjuvant therapy was administered to 62% of upper rectal and 11% of rectosigmoid tumors but only 4% of sigmoid tumors (p-value <0.001). Stage III disease occurred more frequently in rectosigmoid (40%) and upper rectum (55%) cancer than in sigmoid (32%) cancer (p-value <0.001). Lymph node positivity was highest in the upper rectum (57%). Conclusion Significant differences in diagnostic workup and treatment strategies exist across these segments. Rectosigmoid tumors share oncologic characteristics with rectal tumors but are often managed as colonic cancers, highlighting the need for clearer anatomical definitions and treatment guidelines. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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