Improving screening in the WHO ICOPE strategy: lessons from risk profiles for major adverse health outcomes.
Background This study aimed to estimate the risk of four adverse outcomes [disability in instrumental activities of daily living (IADL), institutionalisation, dementia and death] associated with Intrinsic Capacity (IC) impairment at baseline, and to test different combinations of IC impairments to b...
| Publicado en: | Age & Ageing Vol. 55; no. 3; pp. 1 - 10 |
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| Autores principales: | , , , , , , |
| Formato: | Artículo |
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Oxford University Press / USA
Mar2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=192797121&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 192797121 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 00020729 AGA jtl: Age & Ageing issn: 00020729 maglogo: N pubinfo: dt: Mar2026 vid: 55 iid: 3 pid: 622 pub: Oxford University Press / USA artinfo: ui: 192797121 10.1093/ageing/afag051 ppf: 1 ppct: 9 formats: tig: atl: Improving screening in the WHO ICOPE strategy: lessons from risk profiles for major adverse health outcomes. aug: au: Pérès, Karine Jiatsa, Ivane Koumetio Gbessemehlan, Antoine Bardinet, Jeanne Helmer, Catherine Tchalla, Achille Letenneur, Luc affil: University of Bordeaux—Inserm, Bordeaux Population Health Research Center, U1219, Bordeaux, 33076, France University of Limoges Medical Faculty—VieSanté unity, UR 24134, Vieillissement, Fragilité, Prévention, e-Santé—Omega Health Institute, Limoges, France su: World Health Organization Elder care Institutional care Medical screening Hospital care of older people Psychological tests Active aging Activities of daily living Malnutrition diagnosis Hearing disorder diagnosis Senile dementia diagnosis Psychiatric diagnosis Risk assessment Vision disorders Research funding Questionnaires Descriptive statistics Longitudinal method Kaplan-Meier estimator Log-rank test Geriatric assessment Medical care for older people Quality assurance Comparative studies Data analysis software Survival analysis (Biometry) Integrated health care delivery Proportional hazards models Physical mobility sug: subj: Elder care Institutional care Medical screening Hospital care of older people Psychological tests Active aging Activities of daily living World Health Organization Continuing Care Retirement Communities Other Residential Care Facilities Residential Mental Health and Substance Abuse Facilities All Other Miscellaneous Ambulatory Health Care Services Malnutrition diagnosis Hearing disorder diagnosis Senile dementia diagnosis Psychiatric diagnosis Risk assessment Vision disorders Research funding Questionnaires Descriptive statistics Longitudinal method Kaplan-Meier estimator Log-rank test Geriatric assessment Medical care for older people Quality assurance Comparative studies Data analysis software Survival analysis (Biometry) Integrated health care delivery Proportional hazards models Physical mobility keyword: adverse health outcomes copyrightHolder:British Geriatrics Society copyrightYear:2026 healthy ageing https://dx.doi.org/10.1093/ageing/afag051 ICOPE framework inLanguage:en intrinsic capacity older people publisher:Oxford University Press sameAs:https://pubmed.ncbi.nlm.nih.gov/41848760/ adverse health outcomes copyrightHolder:British Geriatrics Society copyrightYear:2026 healthy ageing https://dx.doi.org/10.1093/ageing/afag051 ICOPE framework inLanguage:en intrinsic capacity older people publisher:Oxford University Press sameAs:https://pubmed.ncbi.nlm.nih.gov/41848760/ ab: Background This study aimed to estimate the risk of four adverse outcomes [disability in instrumental activities of daily living (IADL), institutionalisation, dementia and death] associated with Intrinsic Capacity (IC) impairment at baseline, and to test different combinations of IC impairments to better identify high-risk profiles. Methods The sample was drawn from two population-based cohorts (Three-City and AMI), in which the six IC domains were assessed: cognition, nutrition, psychology, hearing, vision and mobility. Participants were categorised into three groups: no impairment (IC0), single impairment (IC1) and two impairments or more (IC2+). Cox models were used to estimate the risk of adverse outcomes associated with IC1 and IC2+ compared to IC0. Conditional inference tree analyses, followed by Cox models, were then conducted to identify the most predictive domains and combinations defining the highest-risk profiles. Results Among the 2964 participants ≥65 included, 24.9% had one IC impairment and 62.3% had two or more. Being in the IC2+ group was associated with a significantly increased risk of all outcomes [adjusted hazard ratios (aHRs) ranging from 2.0 to 3.0], whereas IC1 was not, except for IADL-disability (aHR = 1.46; 95%CI = 1.14–1.87). Mobility, cognitive and visual impairments were constitutive of the highest-risk profiles. Conclusions This study supports the relevance of the ICOPE-targeted IC domains in predicting adverse outcomes. Given the high proportion of individuals screened positive, refining the screening threshold by considering the number and combination of impairments may better identify those who should benefit from the subsequent steps for more advanced assessment or intervention as a priority. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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