Assessment of Dyslipidemia and its Associated Factors Among Non-Alcoholic Fatty Liver Disease Diagnosed Type 2 Diabetes Mellitus Patients in Adama Hospital Medical College: A Cross-Sectional Study.
Background: Dyslipidemia is a condition where lipid metabolism is altered, and its mechanism is closely related to non-alcoholic fatty liver disease. The alteration of lipid metabolism during non-alcoholic fatty liver disease results in disrupted uptake, oxidation, and export. Assessing dyslipidemia...
| Publicado en: | Clinical Medicine Insights: Endocrinology & Diabetes Vol. 19; pp. 1 - 9 |
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| Autores principales: | , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Sage Publications Inc.
4/6/2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=192826172&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 192826172 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 11795514 B3KQ jtl: Clinical Medicine Insights: Endocrinology & Diabetes issn: 11795514 maglogo: Y pubinfo: dt: 4/6/2026 vid: 19 pid: 344 pub: Sage Publications Inc. place: Thousand Oaks, California artinfo: ui: 192826172 192826172 192826172 10.1177/11795514261436946 192826172 ppf: 1 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Assessment of Dyslipidemia and its Associated Factors Among Non-Alcoholic Fatty Liver Disease Diagnosed Type 2 Diabetes Mellitus Patients in Adama Hospital Medical College: A Cross-Sectional Study. aug: au: Feyisa, Mahider Shimelis Eshetu, Bruktawit Arage, Rahel Birhanu Erega, Besfat Berihun Berhan, Ayenew Kiros, Teklehaimanot Mola, Getaneh Enyew, Ermias Bekele affil: Department of Medical Laboratory Sciences, College of Health Sciences, Debre Tabor University, Ethiopia sug: subj: Hyperlipidemia Epidemiology Hyperlipidemia Risk Factors Nonalcoholic Fatty Liver Disease Diabetes Mellitus, Type 2 Academic Medical Centers Human Male Female Middle Age Ethiopia Cross Sectional Studies Random Sample Structured Questionnaires Record Review Anthropometry Blood Pressure Determination Sphygmomanometers Descriptive Statistics Pearson's Correlation Coefficient Multivariate Analysis Logistic Regression Lipoproteins, HDL Cholesterol Lipoproteins, LDL Cholesterol Odds Ratio Confidence Intervals Body Mass Index Immunoassay Data Analysis Software Multivariate Statistics Bivariate Statistics Risk Assessment Middle Aged: 45-64 years Male Female ab: Background: Dyslipidemia is a condition where lipid metabolism is altered, and its mechanism is closely related to non-alcoholic fatty liver disease. The alteration of lipid metabolism during non-alcoholic fatty liver disease results in disrupted uptake, oxidation, and export. Assessing dyslipidemia among non-alcoholic fatty liver disease using these lipid panel is affordable, widely available, and compatible with existing laboratory infrastructure which enables for identifying individuals at increased risk of its complications, guiding therapeutic interventions, and supporting metabolic risk management. Objective: The study aimed to assess Dyslipidemia and its associated factors among non-alcoholic fatty liver disease-diagnosed type 2 diabetes mellitus patients in Adama Hospital Medical College, 2024. Methods: An institution-based cross-sectional study design was used, and the study units were selected using a systematic random sampling technique. Sociodemographic, Behavioral, and Clinical data were collected using a structured questionnaire. Anthropometric measurements were taken by experienced nurses. Fasting venous blood was collected to test the lipid profiles and fasting blood glucose of study participants using Siemens Healthineers dimension EXL 200 chemistry analyzer. Data were assessed using STATA version 17 for correlation analysis among lipid parameters and the predictors, and P <.05 was considered statistically significant. Binary logistic regression was performed to show the statistically significant association among dyslipidemia and associated factors, and P <.05 was also considered statistically significant. Results: The overall proportion of dyslipidemia was found to be 199 (85.04%). High TG 128 (54.7%) and low HDL-C 121 (51.71%) accounts for the major abnormal lipid parameters. BMI, blood pressure, and non-alcoholic fatty liver disease showed a weak positive statistical correlation with increased LDL-C, TG, and TC and a weak negative statistical correlation with HDL-C. The odds of lack of regular exercise and non-alcoholic fatty liver disease were higher for developing dyslipidemia. Conclusions: The overall prevalence of dyslipidemia was found to be high among non-alcoholic fatty liver disease-diagnosed type 2 diabetes mellitus patients. Hypertriglyceridemia was found to be highly prevalent, followed by low HDL-C, and high LDL-C. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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