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Role of the Optometrist in the Management of Bilateral Anterior Lenticonus: A Case of Alport Syndrome.

Background: Alport Syndrome is a rare hereditary clinical condition that causes a disruption in collagen synthesis. It is associated with ocular findings most commonly involving the cornea, lens, and retina. Case Report: An 18-year-old male presented with progressive bilateral vision loss and a hist...

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Published in:Optometry & Visual Performance Vol. 14; no. 1; pp. 32 - 35
Main Authors: Shah, Krishna, Balaji, Janani, Subramanian, Madhumathi
Format: case study pictorial tables/charts Journal Article
Published: Optometric Extension Program Mar2026
Online Access:View this record in EBSCOhost
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      jtl: Optometry & Visual Performance
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    pubinfo:
      dt: Mar2026
      vid: 14
      iid: 1
      pid: 46881
      pub: Optometric Extension Program
      place: Lutherville Timonium, Maryland
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        atl: Role of the Optometrist in the Management of Bilateral Anterior Lenticonus: A Case of Alport Syndrome.
      aug:
        au:
          Shah, Krishna
          Balaji, Janani
          Subramanian, Madhumathi
        affil: Sankara Nethralaya, Chennai, India.
      sug:
        subj:
          Professional Role
          Optometrists
          Nephritis, Hereditary Diagnosis
          Vision Disorders Etiology
          Nephritis, Hereditary Complications
          Lens, Crystalline Abnormalities
          Refractive Errors Therapy
          Contact Lenses
          Male
          Adolescence
          Ophthalmoscopy
          Disease Progression
          Slit Lamp Examination
          Tomography, Optical Coherence
          Corneal Topography
          Genetic Screening
          Visual Acuity
          Refractive Errors
          Adolescent: 13-18 years
          Male
      ab: Background: Alport Syndrome is a rare hereditary clinical condition that causes a disruption in collagen synthesis. It is associated with ocular findings most commonly involving the cornea, lens, and retina. Case Report: An 18-year-old male presented with progressive bilateral vision loss and a history of hypertension and childhood-onset hearing loss. Retinoscopy revealed two distinct reflexes; further evaluation using slit lamp examination and anterior segment optical coherence tomography (AS-OCT) revealed anterior lenticonus. Corneal topography was also performed to rule out keratoconus or other forms of irregular astigmatism; the results were within normal limits, effectively ruling out corneal ectatic disorders. Genetic testing (COL4A5 mutation) was conducted and confirmed the diagnosis of X-linked Alport syndrome. For ocular management, a soft contact lens trial was performed, in which significant improvement in visual acuity was achieved by neutralizing the high myopic reflex from the central lenticonus. Conclusion: This case highlights the importance of detailed retinoscopic assessment and optometric management in Alport syndrome.
      pubtype: Academic Journal
      doctype:
        case study
        pictorial
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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