Improving Access and Recruitment to Clinical Trials for Lung Cancer Patients: A Multi‐Phase, Qualitative Focus Group and Co‐Production Study.

Aim: To design and develop a novel co‐produced intervention tool aimed at facilitating discussions that lung cancer nurses have with lung cancer patients about clinical trial opportunities; and promote trial recruitment. Design: A multi‐phase qualitative focus group (phase 1) and co‐production (phas...

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Publicado en:Journal of Advanced Nursing (John Wiley & Sons, Inc.) Vol. 82; no. 5; pp. 5096 - 5110
Autores principales: Dodd, Christopher, Lond, Benjamin, Davey, Zoe, Williamson, Iain R., Darlison, Liz, Hall, Sally, McPhelim, John, Rawlinson, Janette, Henshall, Catherine
Formato: research tables/charts Journal Article
Publicado: John Wiley & Sons, Inc. May2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2026
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      pub: John Wiley & Sons, Inc.
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        atl: Improving Access and Recruitment to Clinical Trials for Lung Cancer Patients: A Multi‐Phase, Qualitative Focus Group and Co‐Production Study.
      aug:
        au:
          Dodd, Christopher
          Lond, Benjamin
          Davey, Zoe
          Williamson, Iain R.
          Darlison, Liz
          Hall, Sally
          McPhelim, John
          Rawlinson, Janette
          Henshall, Catherine
        affil: Oxford Institute of Applied Health Research, Faculty of Health, Science and Technology, Oxford Brookes University, Oxford, UK
      sug:
        subj:
          Lung Neoplasms
          Clinical Trials
          Patient Participation
          Research Subject Recruitment
          Oncology Nurses Psychosocial Factors
          Nurse-Patient Relations
          Program Development
          Funding Source
          England
          Scotland
          Human
          Male
          Female
          Adult
          Middle Age
          Aged
          Cancer Patients
          Empirical Research
          Action Research
          Qualitative Studies
          Focus Groups
          Caregivers
          Health Personnel
          Purposive Sample
          Multi-Stage Cluster
          Conceptual Framework
          Audiorecording
          Thematic Analysis
          Nursing Knowledge
          Confidence
          Seminars and Workshops
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Aim: To design and develop a novel co‐produced intervention tool aimed at facilitating discussions that lung cancer nurses have with lung cancer patients about clinical trial opportunities; and promote trial recruitment. Design: A multi‐phase qualitative focus group (phase 1) and co‐production (phase 2) study. Methods: The rigorous design and content of the intervention tool was informed by qualitative data from seven focus groups with lung cancer healthcare professionals (n = 38) and patients and their carers (n = 22) to establish barriers and facilitators to clinical trial participation. Data collection took place across England and Scotland between October and December 2023. Findings from a previously published systematic review were also incorporated to inform intervention tool design. The tool was developed through an extended co‐production workshop comprising lung cancer nurses (n = 7), lung cancer patients (n = 2) and health researchers (n = 4). The COM‐B model of behavioural change underpinned both phases of the project to guide tool development. Results: Phase 1 focus groups identified the need for a tool to provide basic trial information to patients, and to support lung cancer nurses in discussing trials with patients, thus improving nurses' knowledge, confidence, and awareness of trials. The phase 2 coproduction workshop identified that the tool should consist of two elements: a patient‐facing information pamphlet and a large poster for nurses to assist them in discussing trial opportunities. Conclusion: The study results demonstrate how nurses can be supported to discuss clinical trial opportunities with patients, with the potential to increase long‐term recruitment to clinical trials. Implications for the Profession and/or Patient Care: Lung cancer nurses often lack confidence to support patients to make informed choices about trial enrolment. By addressing this issue, participation in lung cancer clinical trials can be significantly improved to benefit patient outcomes and trial participation rates. Impact: The tool has the potential to be used across a range of different cancer settings and sites to increase recruitment to clinical trials. Reporting Method: The COREQ checklist was utilised to ensure that robust processes were followed and reported on. Patient and Public Involvement: Patients and members of the public were involved in all study processes and contributed to the study design, interpretation of the data, and intervention design. Their contributions included reviewing focus group topic guides, reviewing data analysis, the co‐production of the intervention tool, and co‐authoring this paper, ensuring the research addressed the needs and priorities of lung cancer patients when making an informed choice about clinical trial participation.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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