Global scale-free brain activity as a potential neural signature of visual information processing in aging.
Introduction: Confluent evidence suggests that aging is associated with a reduction in the spectral slope of neural recordings. This phenomenon has been hypothesized to reflect an increase in the ratio of excitatory and inhibitory (E/I) balance. As neural E/I ratio is considered essential for cognit...
| Publicado en: | Frontiers in Aging Neuroscience pp. 1 - 17 |
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| Autores principales: | , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Frontiers Media S.A.
2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=193010875&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 193010875 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 16634365 BG2U jtl: Frontiers in Aging Neuroscience issn: 16634365 maglogo: N pubinfo: dt: 2026 pid: 40038 pub: Frontiers Media S.A. artinfo: ui: 193010875 193010875 193010875 10.3389/fnagi.2026.1770204 193010875 ppf: 1 ppct: 16 formats: tig: atl: Global scale-free brain activity as a potential neural signature of visual information processing in aging. aug: au: Racz, Frigyes Samuel Kaposzta, Zalan Czoch, Akos Chang, Joshua T. Stylianou, Orestis Mukli, Peter Benge, Jared F. Eke, Andras affil: Department of Neurology, Dell Medical School, The University of Texas at Austin, Austin, TX, United States sug: subj: Cognitive Aging Psychosocial Factors Cognition Disorders In Old Age Brain Physiopathology Executive Function Human Funding Source Male Female Adult Middle Age Aged Aged, 80 and Over Cross Sectional Studies Electroencephalography Community Living Task Performance and Analysis Signal Processing, Computer Assisted Neuropsychological Tests Reaction Time Nervous System Physiology Visual Perception Relaxation Descriptive Statistics Comparative Studies Correlational Studies Pearson's Correlation Coefficient Spearman's Rank Correlation Coefficient Health Services for Older Persons Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: Introduction: Confluent evidence suggests that aging is associated with a reduction in the spectral slope of neural recordings. This phenomenon has been hypothesized to reflect an increase in the ratio of excitatory and inhibitory (E/I) balance. As neural E/I ratio is considered essential for cognitive functioning, this study investigated whether spectral slope (β) predicts cognitive performance in the older adults and could serve as a potential neural signature of cognitive aging. Nevertheless, few studies have examined how spectral slope estimates obtained from both eyes-closed (EC) and eyes-open (EO) resting states relate to cognitive performance in the aging population. Methods: To address this gap, this study analyzed electroencephalography (EEG) recordings of 19 community-dwelling elderly adults (CDE, aged between 60 to 80 years) and 24 young control individuals (YC, aged between 21 to 32 years) collected during EC and EO states. Further, β was estimated from global power spectra after separating scale-free from oscillatory components in the power spectrum. Results: Reduced β was observed in CDE in contrast to YC in both physiological states. While the YC group indicated an increase in β when transitioning from EC to EO, this change could not be observed in CDE. Finally, a strong, anticorrelated relationship between β in EO and performance on a rapid visual information processing task, was typically seen only in the CDE group. Discussion: These results potentially indicate an altered E/I ratio in the CDE cohort, while the inverse relationship with task performance suggests that this pattern could reflect a compensatory brain mechanism supporting cognition during aging. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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