Age and sex disparities in drug shortage impacts: a 10-year nationwide study in France.
Drug shortages are a growing public health issue, unevenly impacting therapeutic classes. Despite variations in drug consumption across populations, the consequences of these shortages on different patient groups remain insufficiently characterized. This study investigated age and sex profiles of pa...
| Publicado en: | European Journal of Public Health Vol. 36; no. 2; pp. 1 - 8 |
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| Autores principales: | , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Oxford University Press / USA
Apr2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=193017713&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 193017713 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 11011262 BHW jtl: European Journal of Public Health issn: 11011262 maglogo: N pubinfo: dt: Apr2026 vid: 36 iid: 2 pid: 622 pub: Oxford University Press / USA artinfo: ui: 193017713 193017713 193017713 10.1093/eurpub/ckag045 193017713 ppf: 1 ppct: 7 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Age and sex disparities in drug shortage impacts: a 10-year nationwide study in France. aug: au: Belgodère, Laëtitia Leleu, Christopher Bacon, Trystan Daynes, Pascale Decoene, Christophe Feugier, Patrick Mazet, Roseline Vial, Thierry Vignot, Stéphane Benkebil, Mehdi affil: Agence Nationale de Sécurité du Médicament et des Produits de Santé (ANSM), Saint Denis, France sug: subj: Healthcare Disparities Evaluation Medication Shortage France Age Factors Sex Factors Human France Female Male Young Adult Adult Middle Age Aged Retrospective Design Secondary Analysis Reimbursement Mechanisms Antiinfective Agents Analgesics Anticonvulsants Vaccines Renin-Angiotensin System T-Tests Wilcoxon Signed Rank Test Post Hoc Analysis Data Analysis Software Descriptive Statistics Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Female Male ab: Drug shortages are a growing public health issue, unevenly impacting therapeutic classes. Despite variations in drug consumption across populations, the consequences of these shortages on different patient groups remain insufficiently characterized. This study investigated age and sex profiles of patients consuming the therapeutic classes most commonly affected by drug shortages in France. The age and sex risk of shortage exposure were estimated in a nationwide retrospective study of French patients between 2014 and 2023, using data from the French drug shortage notification system and the national health insurance for the entire French population. Over 10 years, 17 505 drug shortage reports were recorded, 60.8% involving cardiovascular, nervous system, and anti-infective agents. Significantly higher mean percentages of consumers for drugs concerned by shortage reports per 1000 were observed in ≥60-year-old patients for 12 of the 14 therapeutic classes, compared to 20–59-year-old patients (P = .002). Younger population was more significantly concerned by anti-infective agents (11.2 vs 9.2, P = .002), respiratory system (1.8 vs 1.5, P = .002), and sensory organ (0.7 vs 0.6, P = .002) classes. Significantly higher mean percentages of consumers for drugs concerned by shortage reports per 1000 were observed for all Anatomical Therapeutic Chemical 1st level classes in women (P = .002), but agents acting on the renin–angiotensin system were higher for men (2.32 vs 2.02; P = .002). Our exploratory results suggest that a population-level approach is essential to understand how shortages affect different groups and exacerbate health inequalities. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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