What Is the Role of Biological Sex in the Rehabilitation Path of Elderly Subjects After Total Knee Replacement? A Secondary Analysis of Kinematic and Clinical Data.

Background: The rehabilitation after total knee arthroplasty (TKA) surgery is central; however, the role of sex on the rehabilitation path of subjects after TKA has never been investigated. This study aims to investigate the impact of sex on the improvement rates of clinical outcome scales and gait...

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Publicado en:Topics in Geriatric Rehabilitation Vol. 42; no. 2; pp. 97 - 104
Autores principales: Pullara, Rosa, Buraschi, Riccardo, Grazioli, Marcello, Vicini, Simona, Pedersini, Paolo, Gobbo, Massimiliano, Pollet, Joel
Formato: research tables/charts Journal Article
Publicado: Lippincott Williams & Wilkins Apr-Jun2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr-Jun2026
      vid: 42
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      pub: Lippincott Williams & Wilkins
      place: Baltimore, Maryland
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        atl: What Is the Role of Biological Sex in the Rehabilitation Path of Elderly Subjects After Total Knee Replacement? A Secondary Analysis of Kinematic and Clinical Data.
      aug:
        au:
          Pullara, Rosa
          Buraschi, Riccardo
          Grazioli, Marcello
          Vicini, Simona
          Pedersini, Paolo
          Gobbo, Massimiliano
          Pollet, Joel
        affil: Author Affiliations: IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy (Ms Pullara, Mr Buraschi, Mr Grazioli, Mrs Vicini, Mr Pedersini, Prof. Gobbo, and Mr Pollet)
      sug:
        subj:
          Arthroplasty, Replacement, Knee Rehabilitation
          Arthroplasty, Replacement, Knee Rehabilitation
          Rehabilitation, Geriatric
          Sex Factors
          Knee Joint Physiology
          Kinematics Evaluation
          Treatment Outcomes Evaluation
          Rehabilitation Patients Psychosocial Factors
          Rehabilitation Patients Psychosocial Factors
          Human
          Secondary Analysis
          Male
          Female
          Middle Age
          Aged
          Nonparametric Statistics
          After Care
          Gait
          Funding Source
          Tertiary Health Care
          Rehabilitation Centers
          Inpatients
          Scales
          Data Analysis Software
          Wilcoxon Rank Sum Test
          Post Hoc Analysis
          Linear Regression
          Descriptive Statistics
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Background: The rehabilitation after total knee arthroplasty (TKA) surgery is central; however, the role of sex on the rehabilitation path of subjects after TKA has never been investigated. This study aims to investigate the impact of sex on the improvement rates of clinical outcome scales and gait parameters. Methods: This secondary analysis included subjects after TKA and considered clinical outcome scales, gait spatio-temporal, and summary measures assessed at admission (T0) and discharge (T1). Nonparametric analysis was performed to calculate improvement rates (Δ) and the effect of sex on the considered outcomes. Results: The study included 48 subjects (26 females and 22 males) in the analysis. None of the considered parameters produced significant differences, and the regression analysis also showed no differences; only pain produced a result close to significance (P = .06). Discussion: This study did not show significant differences related to biological sex in the rehabilitation path after TKA. The acute setting of the intervention may have minimized these differences, and a longer follow-up could yield different results. Pain can be influenced by sex, although further studies with more extended follow-ups and larger sample sizes are needed to confirm this hypothesis.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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