Machine learning methods to evaluate fluctuation in oxygenation and peripheral tissue temperature, in sacral and trochanteric area under pressure in healthy subjects and institutionalized patients. A prospective non-randomized trial.

To evaluate the longitudinal changes observed over a period of 120 min in patterns of tissue perfusion, peripheral oxygenation and local temperature of sacral and trochanteric areas exposed to pressure, comparing a healthy population with one at risk of impaired skin integrity. The study protocol is...

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Publicado en:Journal of Tissue Viability Vol. 35; no. 2
Autores principales: Lupiáñez-Pérez, Inmaculada, Muñoz-Lupiáñez, Marina, Gómez-González, Alberto José, Morilla-Herrera, Juan Carlos, Pimentel, Ernesto, Durán, Francisco, García-Luque, Rafael, Marfil-Gómez, Raquel María, Pérez-Ardanaz, Bibiana, Morales-Asencio, José Miguel
Formato: research Journal Article
Publicado: Elsevier B.V. May2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2026
      vid: 35
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      pub: Elsevier B.V.
      place: New York, New York
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        193249343
        193249343
        193249343
        10.1016/j.jtv.2026.100992
        193249343
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        atl: Machine learning methods to evaluate fluctuation in oxygenation and peripheral tissue temperature, in sacral and trochanteric area under pressure in healthy subjects and institutionalized patients. A prospective non-randomized trial.
      aug:
        au:
          Lupiáñez-Pérez, Inmaculada
          Muñoz-Lupiáñez, Marina
          Gómez-González, Alberto José
          Morilla-Herrera, Juan Carlos
          Pimentel, Ernesto
          Durán, Francisco
          García-Luque, Rafael
          Marfil-Gómez, Raquel María
          Pérez-Ardanaz, Bibiana
          Morales-Asencio, José Miguel
        affil: University of Malaga, Faculty of Health Sciences, C/Arquitecto Francisco Peñalosa, 3, Campus Universitario de Teatinos, 29071, Malaga, Spain
      sug:
        subj:
          Machine Learning
          Oxygen Blood
          Skin Temperature
          Sacrum
          Pressure
          Tissue Perfusion Physiology
          Research Subjects
          Institutionalization
          Pressure Ulcer Risk Factors
          Risk Assessment
          Human
          Male
          Female
          Prospective Studies
          Colleges and Universities
          Nursing Homes
          Spectroscopy, Near-Infrared
          Supine Position
          Comparative Studies
          Oxygenation
          Random Forest
          Male
          Female
      ab: To evaluate the longitudinal changes observed over a period of 120 min in patterns of tissue perfusion, peripheral oxygenation and local temperature of sacral and trochanteric areas exposed to pressure, comparing a healthy population with one at risk of impaired skin integrity. The study protocol is registered in ClinicalTrials.gov (NCT02736838). Non-randomised experimental study in two phases. Volunteers were recruited at the University and nursing homes from Nov 2017 to June 2020. The parameters were measured in the sacral and trochanteric areas under pressure using a laser Doppler monitor and near-infrared spectroscopy over 2 h. Body positions varied by area: supine for the sacral region and lateral supine for the trochanteric region. Comparative analysis between both groups of the sacral area showed significant fluctuations in perfusion (p =.035) and local temperature (p =.013). In the trochanteric area, the comparative analysis showed significant fluctuations in perfusion (p =.044), local temperature (p >.001), and oxygenation (p =.049). Nonlinear patterns were identified in the variables examined in both anatomical areas. This prompted the adoption of an algorithm based on the Random Forest Regressor technique to predict the parameters associated with the development of pressure injuries. Individuals at risk of developing pressure injuries show a more limited compensatory physiological response compared to healthy individuals in terms of blood flow, oxygenation, and tissue temperature in pressure areas. Notably, at the 90-min, a turning point is observed, marking a critical threshold from which these parameters begin to decline. • Institutionalized patients show limited microvascular compensatory response. • A 90-min threshold marks decline in perfusion, oxygenation, and temperature. • Simultaneous monitoring reveals non-linear tissue response under pressure. • Random Forest model accurately predicts risk parameters for pressure injuries.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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