'It's more than just irritability': perspectives and experiences of irritability among people affected by Huntington's disease.

Objective: Irritability has been reported as a common psychological co-occurrence with Huntington's disease (HD). Irritability associated with HD is variously attributed to neurological changes, an understandable response to increasing difficulties with cognition and communication, or a multifactori...

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Publicado en:Psychology & Health Vol. 41; no. 5; pp. 674 - 696
Autores principales: Tindall, Tierney, Dale, Maria, Simpson, Jane, Gunn, Sarah
Formato: research tables/charts Journal Article
Publicado: Taylor & Francis Ltd May2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2026
      vid: 41
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      pub: Taylor & Francis Ltd
      place: Philadelphia, Pennsylvania
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        atl: 'It's more than just irritability': perspectives and experiences of irritability among people affected by Huntington's disease.
      aug:
        au:
          Tindall, Tierney
          Dale, Maria
          Simpson, Jane
          Gunn, Sarah
        affil: School of Psychology and Vision Sciences, University of Leicester, Leicester, UK
      sug:
        subj:
          Huntington's Disease Psychosocial Factors
          Affective Disorders Psychosocial Factors
          Patient Attitudes
          Human
          Male
          Female
          Adult
          Middle Age
          Qualitative Studies
          Emotions
          Behavioral Symptoms
          Adaptation, Psychological
          Stress, Psychological
          Quality of Life
          Self Concept
          Thematic Analysis
          Semi-Structured Interview
          Neurodegenerative Diseases
          Mental Disorders
          Interpersonal Relations
          Convenience Sample
          Snowball Sample
          Age Factors
          Race Factors
          Ethnic Groups
          Employment Status
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Objective: Irritability has been reported as a common psychological co-occurrence with Huntington's disease (HD). Irritability associated with HD is variously attributed to neurological changes, an understandable response to increasing difficulties with cognition and communication, or a multifactorial combination of the two or more causes. To improve our understanding, we aimed to explore perspectives and lived experiences of irritability among individuals affected by HD. Methods and measures: Individual semi-structured interviews were conducted with 12 participants (50% female) who were gene-positive for HD. Reflexive thematic analysis was used to analyse the resultant transcripts. Results: Three themes were generated: 'Navigating the complex multifactorial causes of irritability', which reflected participants' perceptions of causes and amplifiers of irritability; 'The tyranny of irritability', which explored how irritability was perceived as powerful and oppressive; and 'Ongoing efforts to resist irritability', which described how participants endeavoured to address irritability. Conclusion: Participants appeared to make sense of irritability as a biopsychosocial experience with multifactorial origins, suggesting the role of attribution theory in understanding their search for meanings and attempts at resistance. Our findings indicate the need to develop meaningful psychological interventions and educational materials to support individuals and their loved ones to understand and address feelings of irritability.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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