Identifying Priority Outcomes for Mothers and Babies in Pregnancies With Preterm Pre‐Labour Rupture of Membranes for Future Clinical Trials.

Preterm pre‐labour rupture of membranes (PPROM) is associated with neonatal and maternal morbidity and mortality. Maternal prophylactic antibiotic therapy after PPROM improves outcomes but there is limited evidence to guide the optimal antibiotic regimen. This study surveyed 45 women with PPROM to u...

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Publicado en:Australian & New Zealand Journal of Obstetrics & Gynaecology Vol. 66; no. 2; pp. 1 - 6
Autores principales: Sathiyaselvan, Ahalya, Dawes, Lisa, Olivier, Nadia, Manley, Brett J., Groom, Katie, Whitehead, Clare L.
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Apr2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2026
      vid: 66
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Identifying Priority Outcomes for Mothers and Babies in Pregnancies With Preterm Pre‐Labour Rupture of Membranes for Future Clinical Trials.
      aug:
        au:
          Sathiyaselvan, Ahalya
          Dawes, Lisa
          Olivier, Nadia
          Manley, Brett J.
          Groom, Katie
          Whitehead, Clare L.
        affil: Liggins Institute, University of Auckland, Auckland, New Zealand
      sug:
        subj:
          Expectant Mothers Psychosocial Factors
          Fetal Membranes, Premature Rupture Complications
          Labor, Premature Complications
          Antibiotics Therapeutic Use
          Pregnancy Outcomes Evaluation
          Pregnancy Complications Prevention and Control
          Clinical Trials
          Patient Participation
          Decision Making
          Research Subject Recruitment
          Human
          Funding Source
          New Zealand
          Australia
          Female
          Adolescence
          Adult
          Middle Age
          Prospective Studies
          Descriptive Statistics
          Pregnancy
          Tertiary Health Care
          Multicenter Studies
          Brain Injuries Prevention and Control
          Infant Mortality Prevention and Control
          Respiratory System
          Health Status In Infancy and Childhood
          Infant
          Child
          Adolescent: 13-18 years
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Infant: 1-23 months
          Child: 6-12 years
          Female
      ab: Preterm pre‐labour rupture of membranes (PPROM) is associated with neonatal and maternal morbidity and mortality. Maternal prophylactic antibiotic therapy after PPROM improves outcomes but there is limited evidence to guide the optimal antibiotic regimen. This study surveyed 45 women with PPROM to understand consumer priorities for care, maternal and neonatal outcomes; and inform future PPROM clinical trial design. The highest priorities were prolonging gestation, avoiding brain injury, improving neonatal survival and good childhood respiratory health. Seventy‐nine percent of respondents would consider clinical trial participation. Identifying consumer priorities will support both trial design and improved clinical care.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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