Addressing wound healing barriers to optimise wound progression: investigating the advanced benefits of a next-generation multilayer foam dressing.
Objective: Excess wound exudate can cause tissue maceration and delayed healing. Fluctuating exudate levels, combined with the impact of gravity, increase dressing leakage risk, affecting patient quality of life. Bacteria and proteases found in hard-to-heal (chronic) wounds pose additional barriers...
| Publicado en: | Journal of Wound Care Vol. 35; no. 5; pp. 365 - 377 |
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| Autores principales: | , , , , , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Mark Allen Holdings Limited
May2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=193414527&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 193414527 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09690700 H3U jtl: Journal of Wound Care issn: 09690700 maglogo: N pubinfo: dt: May2026 vid: 35 iid: 5 pid: 11383 pub: Mark Allen Holdings Limited artinfo: ui: 193414527 193414527 193414527 10.12968/jowc.2026.0135 193414527 ppf: 365 ppct: 12 formats: tig: atl: Addressing wound healing barriers to optimise wound progression: investigating the advanced benefits of a next-generation multilayer foam dressing. aug: au: Ousey, Karen Garba, Kamaluddeen Lwaleed, Bashir Fitzgerald, Daniel Williams, Damaris Winks, Jessica Brownhill, Varuni Worsley, Peter affil: University of Huddersfield, UK sug: subj: Wound Healing Wound Care Methods Foam Dressings Wounds, Chronic Therapy Exudates and Transudates Product Evaluation Silicones Polyurethanes In Vitro Studies Experimental Studies Comparative Studies Models, Biological Gravitation Bacteria Matrix Metalloproteinases Confidence Equipment Design Equipment Reliability T-Tests Wilcoxon Rank Sum Test Post Hoc Analysis Unpaired T-Tests One-Way Analysis of Variance Descriptive Statistics Data Analysis Software Funding Source Occlusive Dressings ab: Objective: Excess wound exudate can cause tissue maceration and delayed healing. Fluctuating exudate levels, combined with the impact of gravity, increase dressing leakage risk, affecting patient quality of life. Bacteria and proteases found in hard-to-heal (chronic) wounds pose additional barriers to healing if not promptly removed. Absorbent dressings must therefore address these multiple challenges, and so were explored in this series of preclinical investigations. Method: Standard in vitro absorbency tests were conducted to compare the performance of several dressings with a new advanced five-layer silicone polyurethane foam dressing with superabsorbent particles (ASFS). Dressing functionality was explored using clinically relevant test conditions, including the impact of gravity and fluid bolus events on absorbency, combined with the dressing's ability to absorb and retain bacteria and proteases. Results: ASFS demonstrated superior performance across standard absorbency tests versus most of the alternative absorbent dressings and outperformed a comparator five-layer silicone foam dressing with superabsorbent fibres (SFD) in run-off testing. Under clinically relevant dynamic bolus conditions, including gravitational challenge, no leakage was observed with ASFS, whereas dressing failure due to fluid spill or leakage was observed with SFD. ASFS was also shown to retain matrix metalloproteinases and the majority of bacteria, even under increasing fluid volumes. Conclusion: Functionality of absorbent wound dressings in both standard and clinically relevant tests is critical to support healthcare professionals' decision-making in selecting optimal interventions for their patients' wounds. Effective exudate management combined with removal of bacteria and proteases by the new ASFS dressing supports healthcare professional and patient confidence in continuing with daily activities, with the potential for fewer dressing changes and associated resource benefits, warranting further evaluation in clinical practice. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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