Life Years Gained and Healthcare Dollars Saved: National Economic Evidence Supporting Comprehensive Genomic Profiling as Standard of Care for Canadian Cancer Patients.
Simple Summary: In 2025, the Colorectal Cancer Resource & Action Network (CCRAN)'s hosted their virtual Biomarkers Conference as a forum for clinicians, scientists, and patients to discuss the clinical value of comprehensive genomic profiling (CGP) for individuals with metastatic cancer and overcomi...
| Published in: | Current Oncology Vol. 33; no. 4; pp. 191 - 203 |
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| Main Authors: | , , , , , , , , , , |
| Format: | Journal Article |
| Published: |
MDPI
Apr2026
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=193441184&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 193441184 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 11980052 5EKK jtl: Current Oncology issn: 11980052 maglogo: N pubinfo: dt: Apr2026 vid: 33 iid: 4 pid: 97109 pub: MDPI artinfo: ui: 193441184 10.3390/curroncol33040191 193441184 ppf: 191 ppct: 12 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Life Years Gained and Healthcare Dollars Saved: National Economic Evidence Supporting Comprehensive Genomic Profiling as Standard of Care for Canadian Cancer Patients. aug: au: Snow, Stephanie Banerji, Shantanu Bombard, Yvonne Husereau, Don Karamchandani, Jason Nason, Eddy Ohashi, Pamela S. van Rooijen, Gijs Vainer, Gilad Macaulay, Cassandra Servidio-Italiano, Filomena affil: Queen Elizabeth II Health Sciences Centre, Halifax, NS B3H 2Y9, Canada sug: ab: Simple Summary: In 2025, the Colorectal Cancer Resource & Action Network (CCRAN)'s hosted their virtual Biomarkers Conference as a forum for clinicians, scientists, and patients to discuss the clinical value of comprehensive genomic profiling (CGP) for individuals with metastatic cancer and overcoming barriers to access. The keynote presentation was of the first national costs and benefits analysis of universal CGP for five metastatic tumour types; findings estimated a gain of 3440 life years and $87M–134M of potential healthcare system savings, over a six-year period. Conference sessions focused on strategies to leverage these results while learning from international experiences, in addition to mechanisms to facilitate CGP access in Canada. Several calls to action were recommended: a national strategy to reduce disparities in equitable CGP access, allocation of funding for CGP as a standard of care for all patients with metastatic cancer, and methods to enhance current infrastructure to facilitate progress. Comprehensive genomic profiling (CGP) is a meaningful advancement in the field of oncology, enabling critical clinical decision-making regarding precision treatments that have biological rationale. In June 2025, the Colorectal Cancer Resource & Action Network (CCRAN) hosted their annual pan-tumour Biomarkers Conference, a virtual meeting of clinicians, scientists, and patients, to discuss recent progress in overcoming barriers to CGP access for patients in Canada with metastatic cancer. The meeting's cornerstone was the presentation of the first national costs and benefits analysis of universal CGP for five metastatic tumour types; findings demonstrated this diagnostic's potential, with the model estimating a gain of 3440 life years while generating $87M–134M of potential healthcare system savings, over a six-year time horizon. Additionally, conference sessions focused on the clinical value of CGP, strategies to leverage the economic analysis results and learn from international experiences, as well as mechanisms to prepare the Canadian healthcare system for future adoption. The conference led to calls to action for a national strategy to reduce disparities in equitable access to CGP, funding allocation for CGP as a standard of care for all patients with metastatic cancer, and pathways to enhance current infrastructure to expedite CGP across the country. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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