Trajectories of frailty, grip strength and gait speed preceding dementia: a nested case–control study.

Background Functional decline may be an early indicator of dementia. This study examined the trajectories of frailty, grip strength, and gait speed over the 11 years prior to dementia, compared to matched individuals without dementia. Methods A total of 1092 dementia cases were matched on age, sex a...

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Publicado en:	Age & Ageing Vol. 55; no. 4; pp. 1 - 11
Autores principales:	Wu, Zimu, Phyo, Aung Zaw Zaw, Cribb, Lachlan, Vishwanath, Swarna, Orchard, Suzanne G, Owen, Alice, Woods, Robyn, Chong, Trevor T-J, Wolfe, Rory, Shah, Raj C
Formato:	Artículo
Publicado:	Oxford University Press / USA Apr2026
Materias:	Australia United States Mental health Sex distribution Age distribution Classification of mental disorders Case-control method Quality of life Physical fitness Cognition Activities of daily living Dementia risk factors Dementia prevention Risk assessment Independent living Research funding T-test (Statistics) Frail elderly Brain Gait in humans Functional status Chi-squared test Descriptive statistics Muscle strength Longitudinal method Geriatric assessment Apolipoproteins Neuropsychological tests Walking speed Exercise tests Early diagnosis Body movement Data analysis software Grip strength Time Regression analysis Muscle contraction Genotypes Biomarkers
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