Pathway-level insights into the epigenetic ageing of human skin.

Skin ageing emerges from the interplay of intrinsic biological decline, environmental exposures and disease-related remodelling, yet the pathway-level epigenetic programs that integrate these processes remain largely unresolved. Here, we develop a skin-specific PathwayAge clock that aggregates DNA m...

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Bibliographic Details

Published in:	Age & Ageing Vol. 55; no. 4; pp. 1 - 11
Main Authors:	Jiang, Jindou, Li, Pan, Zhu, Jijun, Cai, Fuqiang, Wang, Shenghan, Huang, Zhongting, Zhang, Shunjie, Zhou, Fusheng, Zhong, Wenwei, Chen, Junfang
Format:	Article
Published:	Oxford University Press / USA Apr2026
Subjects:	Case-control method Genome-wide association studies Research funding Epigenomics Logistic regression analysis Mann Whitney U Test DNA methylation Machine learning Skin aging Overall survival Proportional hazards models Evaluation
Online Access:	View this record in EBSCOhost