Dual inhibition of PI3K and mTOR in cancer therapy: Mechanisms, clinical potential, and future perspectives.

The PI3K/AKT/mTOR signaling system is essential for controlling cell growth, survival, proliferation, and metabolism, rendering it a significant therapeutic target in cancer treatment. Dysregulation of this system is commonly reported in numerous cancers, facilitating tumor development and resistanc...

Full description

Bibliographic Details
Published in:Pharmacy Practice (1886-3655) Vol. 24; no. 1; pp. 1 - 14
Main Authors: Al Anta, Tasneem, Al Shehadat, Ola, Taneera, Jalal, Aleidi, Shereen M., Abuhelwa, Ahmad A., Alzoubi, Karem H., Semreen, Mohammad H., El-Huneidi, Waseem, Abu-Gharbieh, Eman, Bustanji, Yasser
Format: review tables/charts Journal Article
Published: Centro de Investigaciones y Publicaciones Farmaceuticas S.L. Jan-Mar2026
Online Access:View this record in EBSCOhost