Working Memory Performance is Reduced after a Marathon Race and Associated with Low Energy Availability in Females.

Purpose: We tested the hypothesis that marathon racing reduces working memory performance and increases frontal theta activity in trained female endurance athletes. We further examined whether changes in cognitive performance or brain activity were associated with either acute and/or chronic risk of...

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Publicado en:Medicine & Science in Sports & Exercise Vol. 58; no. 6; pp. 1246 - 1259
Autores principales: BOERE, KATHERINE, YOUNG, NEVAN, DAUPHINEE, RAE, COPITHORNE, FRANCES, KIRBY, BRETT S., KRIGOLSON, OLAVE E., STELLINGWERFF, TRENT
Formato: research tables/charts Journal Article
Publicado: Lippincott Williams & Wilkins Jun2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2026
      vid: 58
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      pub: Lippincott Williams & Wilkins
      place: Baltimore, Maryland
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        10.1249/MSS.0000000000003937
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        atl: Working Memory Performance is Reduced after a Marathon Race and Associated with Low Energy Availability in Females.
      aug:
        au:
          BOERE, KATHERINE
          YOUNG, NEVAN
          DAUPHINEE, RAE
          COPITHORNE, FRANCES
          KIRBY, BRETT S.
          KRIGOLSON, OLAVE E.
          STELLINGWERFF, TRENT
        affil: The Department of Exercise Science, Physical & Health Education, University of Victoria, Victoria, British Columbia, CANADA
      sug:
        subj:
          Athletes, Female
          Memory, Short Term Evaluation
          Running, Distance
          Frontal Lobe Physiology
          Cognition
          Risk Assessment
          Energy Intake
          Energy Metabolism
          Human
          Female
          Questionnaires
          Funding Source
          Victoria
          British Columbia
          Surveys
          Adult
          Middle Age
          Task Performance and Analysis
          Reaction Time
          Validity
          Electroencephalography
          Mobile Applications
          Oxygen Consumption
          Anthropometry
          Sporting Events
          Body Mass Index Evaluation
          Fluid Intake Evaluation
          Pretest-Posttest Design
          Repeated Measures
          Two-Way Analysis of Variance
          Two-Tailed Test
          Paired T-Tests
          Post Hoc Analysis
          Pearson's Correlation Coefficient
          Bivariate Statistics
          Multiple Linear Regression
          Data Analysis Software
          Dietary Carbohydrates Analysis
          Time Factors
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Female
      ab: Purpose: We tested the hypothesis that marathon racing reduces working memory performance and increases frontal theta activity in trained female endurance athletes. We further examined whether changes in cognitive performance or brain activity were associated with either acute and/or chronic risk of low energy availability. Methods: Sixteen female Tier 2 runners (42 ± 9 yr; VO2max 45.6 ± 6 mL·kg−¹·min−¹) underwent VO2max testing and the Low Energy Availability in Females Questionnaire (LEAF-Q) 7–14 d before a marathon. Participants completed 1-back (low-load) and 3-back (high-load) working memory tasks during electroencephalogram recordings, performed before and immediately after the race (<10 min). Accuracy and reaction time measured cognitive performance, and frontal theta power measured cognitive effort. Results: Sixteen runners completed the marathon in 4:16 ± 37 min (70 ± 6% VO2max), with a mean carbohydrate intake of 28 ± 14 g·h−1. Six athletes exceeded the LEAF-Q threshold (≥8) and eight reported menstrual dysfunction. Postrace, 3-back accuracy declined (−18.8%, P = 0.003) while reaction time shortened for both task versions (5.3%–6.6%, P = 0.002). Frontal theta increased postrace (1-back: +26.8%; 3-back: +29.6%, P < 0.001). Regression models showed that 3-back accuracy changes were predicted by LEAF-Q score (β = 0.494, P = 0.016). In contrast, theta increases were predicted by a combination of lower carbohydrate intake (β = −0.025, P = 0.005), longer race time (β = 0.008, P = 0.005), and higher LEAF-Q score (β = 0.121, P < 0.001). Conclusions: Working memory performance is reduced and cognitive effort is increased after marathon racing in trained female athletes. These effects are linked to both acute and chronic risk of low energy availability, emphasizing the need for individualized fueling strategies to preserve cognitive performance during endurance events.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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