Penile pyoderma gangrenosum mimicking phagedenic chancroid: An enigma of genital ulcer.
Pyoderma gangrenosum (PG) is an uncommon neutrophilic dermatosis that typically presents with painful ulcerative lesions, most often on the lower extremities. Genital involvement, particularly of the penis, is extremely rare and may clinically resemble infectious or necrotizing ulcers, leading to de...
| Publicado en: | Indian Journal of Sexually Transmitted Diseases & AIDS Vol. 47; no. 1; pp. 65 - 68 |
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| Autores principales: | , , , |
| Formato: | case study pictorial tables/charts Journal Article |
| Publicado: |
Wolters Kluwer India Pvt Ltd
Jan-Jun2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=193860473&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 193860473 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 25890557 MV1S jtl: Indian Journal of Sexually Transmitted Diseases & AIDS issn: 25890557 maglogo: N pubinfo: dt: Jan-Jun2026 vid: 47 iid: 1 pid: 16919 pub: Wolters Kluwer India Pvt Ltd artinfo: ui: 193860473 193860473 193860473 10.4103/ijstd.ijstd_187_25 193860473 ppf: 65 ppct: 3 formats: tig: atl: Penile pyoderma gangrenosum mimicking phagedenic chancroid: An enigma of genital ulcer. aug: au: Dongre, Atul M. Kamble, Pramod Dhanraj Nayak, Chitra Hiray, Amruta affil: Department of Dermatology, Topiwala National Medical College and BYL Nair Hospital, Mumbai, Maharashtra, India sug: subj: Penis Pathology Ulcer Etiology Pyoderma Gangrenosum Diagnosis Chancroid Diagnosis Diagnosis, Differential Adult Male Ulcer Pathology Pyoderma Gangrenosum Drug Therapy Adrenal Cortex Hormones Therapeutic Use Methotrexate Therapeutic Use Treatment Outcomes Adult: 19-44 years Male ab: Pyoderma gangrenosum (PG) is an uncommon neutrophilic dermatosis that typically presents with painful ulcerative lesions, most often on the lower extremities. Genital involvement, particularly of the penis, is extremely rare and may clinically resemble infectious or necrotizing ulcers, leading to delays in diagnosis and inappropriate management. We report a 22-year-old uncircumcised male who presented with a progressive, painful penile ulcer unresponsive to multiple antibiotic courses. Clinical examination revealed a deep ulcer with irregular, undermined edges and purulent slough. Routine laboratory investigations, serology for sexually transmitted infections, wound cultures, and systemic evaluation were unremarkable. Histopathology demonstrated dense neutrophilic infiltration with granulomatous features, and a pathergy test was positive. The patient responded rapidly to oral corticosteroid therapy, with methotrexate introduced as a steroid-sparing agent, achieving complete healing within 8 weeks. This case underscores the importance of considering PG in persistent penile ulcers to enable timely immunosuppressive therapy and avoid mutilating surgical procedures. pubtype: Academic Journal doctype: case study pictorial tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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