Clinical and Cost-Effectiveness Analysis of a Silicone Multilayer Foam Dressing for Pressure Injury Prevention: A Systematic Literature Review and Meta-Analysis.

Supplemental Digital Content is Available in the Text. PURPOSE: The purpose of this systematic review was to determine the clinical and economic impact of using a silicone multilayer foam dressing in the prevention of sacral pressure injuries (PIs) in at-risk patients. METHOD: Systematic literature...

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Publicado en:Journal of Wound, Ostomy & Continence Nursing Vol. 53; no. 3; pp. 205 - 213
Autores principales: Pittman, Joyce, Constable, Stephanie, Costa, Ben, Askew, Neil, Atkinson, Lloyd
Formato: meta analysis research systematic review tables/charts Journal Article
Publicado: Lippincott Williams & Wilkins May/Jun2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May/Jun2026
      vid: 53
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      pub: Lippincott Williams & Wilkins
      place: Baltimore, Maryland
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        193864813
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        10.1097/WON.0000000000001286
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        atl: Clinical and Cost-Effectiveness Analysis of a Silicone Multilayer Foam Dressing for Pressure Injury Prevention: A Systematic Literature Review and Meta-Analysis.
      aug:
        au:
          Pittman, Joyce
          Constable, Stephanie
          Costa, Ben
          Askew, Neil
          Atkinson, Lloyd
        affil: Joyce Pittman, PhD, ANP-BC, FNP-BC, CWOCN, WOCNF, FAAN, College of Nursing, University of South Alabama, Mobile, Alabama.
      sug:
        subj:
          Cost Benefit Analysis Evaluation
          Silicones Therapeutic Use
          Foam Dressings Economics
          Sacrum Injuries
          Pressure Ulcer Prevention and Control
          Treatment Outcomes
          Human
          Funding Source
          Systematic Review
          Meta Analysis
          Italy
          Australia
          Embase
          PubMed
          Cochrane Library
          Checklists
          Odds Ratio
          Confidence Intervals
          Cost Savings
          Health Care Costs
          Pressure Ulcer Risk Factors
          Risk Assessment
      ab: Supplemental Digital Content is Available in the Text. PURPOSE: The purpose of this systematic review was to determine the clinical and economic impact of using a silicone multilayer foam dressing in the prevention of sacral pressure injuries (PIs) in at-risk patients. METHOD: Systematic literature review and meta-analysis. SEARCH STRATEGY: Literature was obtained through EMBASE, PubMed, and Cochrane Library between January 2010 and October 2023. Inclusion criteria were randomized controlled trials that compared a silicone multilayer foam dressing with standard prevention (SP) care in the intervention arm, or SP alone as a comparator in the control arm. Study quality and risk of bias were assessed using the Risk of Bias 2 (RoB2) instrument. FINDINGS: A total of 781 records were identified, and data were extracted from 3 studies. The pooled sample comprised 589 participants receiving SP versus 561 patients receiving SP plus multilayer dressing across various hospital settings. Meta-analysis revealed a 66% reduction in the odds of PI among patients receiving SP plus the dressing when compared with SP alone (odds ratio, 0.34, 95% confidence interval, 0.22-0.54). Subanalysis of stage 1 and stage ≥2 PIs confirmed the stability of these findings and resulted in an estimated cost saving of $1,925 per patient; this finding was stable under both one-way and probabilistic sensitivity analyses. IMPLICATIONS: Findings from this meta-analysis supports the clinical and economic benefits of implementing multilayer foam dressings into existing care bundles in the prevention of PIs in at-risk patients.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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