Associations of Autistic Traits and Autism with Incontinence and Constipation in a UK Birth Cohort.

There is evidence that children with autism/autistic traits have higher risks of incontinence and constipation, but no studies have examined this in a large community-based cohort. Aim/Research question: are autistic traits and diagnosed autism prospectively associated with increased odds of inconti...

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Publicado en:Journal of Autism & Developmental Disorders Vol. 56; no. 5; pp. 1999 - 2009
Autores principales: Gyamenah, Prince, Burrows, Kimberley, Rai, Dheeraj, Joinson, Carol
Formato: research tables/charts Journal Article
Publicado: Springer Nature May2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2026
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      pub: Springer Nature
      place: New York, New York
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        atl: Associations of Autistic Traits and Autism with Incontinence and Constipation in a UK Birth Cohort.
      aug:
        au:
          Gyamenah, Prince
          Burrows, Kimberley
          Rai, Dheeraj
          Joinson, Carol
        affil: https://ror.org/0524sp257 Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK
      sug:
        subj:
          Autism Spectrum Disorder Complications
          Incontinence Risk Factors
          Incontinence Risk Factors
          Constipation Risk Factors
          Constipation Risk Factors
          Human
          Autism Spectrum Disorder Diagnosis
          Prospective Studies
          United Kingdom
          Child
          Adolescence
          Medical Records
          International Classification of Diseases
          Multivariate Analysis
          Logistic Regression
          Descriptive Statistics
          Chi Square Test
          Data Analysis Software
          Checklists
          Funding Source
          Communicative Disorders Complications
          Sense of Coherence
          Phenotype
          Questionnaires
          Documentation
          Enuresis Risk Factors
          Fecal Incontinence Risk Factors
          Autism Spectrum Disorder Physiopathology
          Child: 6-12 years
          Adolescent: 13-18 years
      ab: There is evidence that children with autism/autistic traits have higher risks of incontinence and constipation, but no studies have examined this in a large community-based cohort. Aim/Research question: are autistic traits and diagnosed autism prospectively associated with increased odds of incontinence and constipation in children and adolescents? This was a population-based cohort study based on data from the Avon Longitudinal Study of Parents and Children (n = 4233–4490 at age 9 years; n = 3403–3697 at age 14). We used multivariable logistic regression to examine associations of parent-reported autistic traits (sociability, repetitive behaviours, social-communication, coherence) (at ages 3–9 years) and autism with incontinence (bedwetting, daytime-wetting, soiling) and constipation (parent-reported at age 9, self-reported at age 14). We adjusted for parity, maternal age at delivery, child's sex and developmental level, maternal depression, and anxiety (antenatal and postnatal), and indicators of family socioeconomic status. Social-communication and speech coherence difficulties showed the strongest associations with incontinence, e.g., adjusted odds ratio (OR) and 95% confidence interval (CI) for the association between social-communication difficulties and daytime-wetting was 2.21 (1.47–3.32) and for coherence was 2.34 (1.60–3.43). The odds of soiling were also higher in children with social-communication (OR: 1.88, 95% CI 1.28–2.75) and coherence difficulties (OR: 2.04, 95% CI 1.43–2.93). Diagnosed autism was only associated with an increase in the odds of daytime-wetting (OR: 3.18, 95% CI 1.44–7.02). At 14 years, there was less evidence of associations between autistic traits and incontinence but there was evidence of associations between autistic traits and constipation: social-communication (OR: 1.68, 95% CI 1.13–2.49), coherence difficulties (OR: 1.64, 95% CI 1.11–2.41). Early assessment and treatment of incontinence/constipation should be considered for children with autistic traits.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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