Developing a CRISPR/Cas9 Plasmid Vector Containing Specific Single Guide RNAs Targeting SMO in the Sonic Hedgehog Signaling Pathway for SHH-Driven Cancers.

Background & Objective: Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) system is considered an efficient tool for genomic engineering in the field of cancer/gene therapy. Developing a plasmid vector to target the signaling pathway of sonic hedgehog (SHH),...

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Bibliographic Details

Published in:	Journal of Advances in Medical & Biomedical Research Vol. 34; no. 1; pp. 23 - 31
Main Authors:	Ghorbanlou, Mehrdad, Salimi-Jeda, Ali, Razavi, Mohamad Reza, Shabani, Ronak, Moradi, Fatemeh, Marzban, Hassan, Mehdizadeh, Mehdi
Format:	pictorial research tables/charts Journal Article
Published:	Zanjan University of Medical Sciences & Health Services Jan/Feb2026
Online Access:	View this record in EBSCOhost