ADAPTIVE FEATURE FUSION AND CONFIDENCE-AWARE ENSEMBLE LEARNING FOR AUTOMATED BREAST CANCER GRADING.

Manual evaluation of mitotic activity & nuclear atypia is laborious and prone to inter-observer variability; yet, accurate classification of breast cancer using histopathological pictures is essential for diagnosis and therapy planning. Automatic cancer of the breast grading using the MITOS-ATYPIA-1...

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Publicado en:Scientific Culture Vol. 12; no. 5; pp. 296 - 308
Autores principales: Maheshwari, Neerudu Uma, SatheesKumaran, S.
Formato: Artículo
Publicado: University of the Aegean 2026
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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        atl: ADAPTIVE FEATURE FUSION AND CONFIDENCE-AWARE ENSEMBLE LEARNING FOR AUTOMATED BREAST CANCER GRADING.
      aug:
        au:
          Maheshwari, Neerudu Uma
          SatheesKumaran, S.
        affil: Department of Electronics and Communication Engineering, Anurag University, Hyderabad, India
      su:
        Tumor grading
        Data fusion (Statistics)
        Ensemble learning
        Classification algorithms
        Computer-assisted image analysis (Medicine)
        Image segmentation
        Cell cycle
        Cell nuclei
      sug:
        subj:
          Tumor grading
          Data fusion (Statistics)
          Ensemble learning
          Classification algorithms
          Computer-assisted image analysis (Medicine)
          Image segmentation
          Cell cycle
          Cell nuclei
      keyword:
        Attention mechanism
        Breast cancer grading
        Computer-aided diagnosis
        Deep learning
        Histopathological image analysis
        multi-task learning
      ab: Manual evaluation of mitotic activity & nuclear atypia is laborious and prone to inter-observer variability; yet, accurate classification of breast cancer using histopathological pictures is essential for diagnosis and therapy planning. Automatic cancer of the breast grading using the MITOS-ATYPIA-14 dataset is presented in this research utilising an ambiguously guided dual-branch hybrid architecture. Hybrid nuclei segmentation with U-Net and watersheds algorithms follows stain normalisation and contrast enhancement in the suggested approach. Mitotic or nuclear atypia features are extracted separately using a dual-branch feature learning technique that combines profound learning, structural morphology, and texture-based descriptors. The most discriminative characteristics are selected using an attention-based dynamic feature selection technique and then merged to create a complete representation. An ensemble model that incorporates Support Vector Machine, Random Forest, & Light GBM is used for classification in order to increase accuracy and resilience. By integrating mitotic & atypia scores using a modified grading method, the ultimate cancer grade is determined. The experimental findings show that the suggested framework outperforms the current methods, with a 97.82% accuracy and a 96.77% F1-score. Based on these outcomes, it seems like the suggested approach is a solid bet for automatic breast cancer grading.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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