Clinical Factors Associated With Patterns of Medication Errors Among Pediatric Hospitalized Patients in Northwest Ethiopia: A Multicenter Prospective Observational Study.
Background: Medication safety is an important public health challenge, especially in pediatrics. Medication errors (MEs) are often underreported in pediatrics and can lead to adverse outcomes such as frequent readmissions, increased total healthcare costs, prolonged hospitalization, and related morb...
| Publicado en: | BioMed Research International Vol. 2026; pp. 1 - 12 |
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| Autores principales: | , , , , , , , , |
| Formato: | equations & formulas research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
5/23/2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=193980928&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 193980928 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23146133 FT2T jtl: BioMed Research International issn: 23146133 maglogo: N pubinfo: dt: 5/23/2026 vid: 2026 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 193980928 193980928 193980928 10.1155/bmri/8893135 193980928 ppf: 1 ppct: 11 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Clinical Factors Associated With Patterns of Medication Errors Among Pediatric Hospitalized Patients in Northwest Ethiopia: A Multicenter Prospective Observational Study. aug: au: Moges, Tilaye Arega Dagnew, Fisseha Nigussie Tarekegn, Getachew Yitayew Wondm, Samuel Agegnew Zewdu, Woretaw Sisay Anberbr, Sisay Sitotaw Nigussie, Habtamu Dagnew, Samuel Berihun Klug, Yoel A. affil: Department of Clinical Pharmacy,, Pharmacy Education and Clinical Services Directorate,, Debre Tabor University,, Debre Tabor, Ethiopia, dtu.edu.et sug: subj: Medication Errors Epidemiology Medication Errors Risk Factors Pediatrics Child, Hospitalized Psychosocial Factors Hospitals, Special Risk Assessment Human Male Female Child Ethiopia Multicenter Studies Prospective Studies Nonexperimental Studies Polypharmacy Inpatients Length of Stay Sex Factors Antibiotics Patient Safety Drug Administration Schedule Chi Square Test Multivariate Analysis Multiple Logistic Regression Bivariate Statistics Odds Ratio Confidence Intervals Statistical Significance Data Analysis Software Descriptive Statistics Child: 6-12 years Male Female ab: Background: Medication safety is an important public health challenge, especially in pediatrics. Medication errors (MEs) are often underreported in pediatrics and can lead to adverse outcomes such as frequent readmissions, increased total healthcare costs, prolonged hospitalization, and related morbidity and mortality. Thus, this study is aimed at assessing the magnitude and determinants of MEs among pediatric hospitalized patients at comprehensive specialized hospitals in Northwest Ethiopia. Methods: A multicenter prospective observational study involving pediatric hospitalized patients was conducted over 4 months, utilizing systematic random sampling for participant selection. Three clinical pharmacists, after a day of training, collected data under the supervision of an MSc health professional, with support from pediatricians in each hospital for reviewing MEs and adjusting treatment plans. Pediatric patients were followed prospectively during their hospital stay from admission to discharge. Data collection occurred via the Kobo Toolbox platform and was analyzed with STATA Version 17.0. Both bivariate and multivariable logistic regression analyses identified factors related to MEs, with statistical significance set at a p value < 0.05. Results: Among 358 pediatric hospitalized patients, 53.63% experienced at least one ME, totaling 254 identified errors. The prescribing stage accounted for the highest percentage of errors (40.16%), followed by the administration stage (32.68%). The predominant types of MEs were dose errors (30.31%), frequency errors (14.96%), and omission errors (14.17%). Multivariable logistic regression analysis revealed that polypharmacy (≥ 5 medications) (AOR = 2.005, 95% CI: 1.269–3.168), male sex (AOR = 1.707, 95% CI: 1.097–2.656), and prolonged hospital stay (AOR = 1.673, 95% CI: 1.076–2.602) were significantly associated with the occurrence of MEs. Conclusion: This study found that MEs were prevalent in pediatric hospitalized patients. Polypharmacy, male patients, and the length of hospital stay were independent predictors of MEs. To reduce MEs, computer‐based prescribing practice and clinical pharmacy services should be routine practices in the study settings. pubtype: Academic Journal doctype: equations & formulas research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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