Pharmacokinetics, Safety, and Tolerability of Anti‐miR‐17 Oligonucleotide RGLS4326 in Healthy Adult Subjects.

Autosomal dominant polycystic kidney disease (ADPKD) is the most common form of polycystic kidney disease in adults and is characterized by progressive renal cyst formation and enlargement of the kidneys. The expression of microRNA‐17 (miR‐17) family is increased in kidney samples from ADPKD patient...

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Publicado en:Journal of Clinical Pharmacology Vol. 66; no. 5; pp. 1 - 17
Autores principales: Owen, Tate, Cole, Izaiah, Drygin, Denis, Valencia, Tania, Lee, Edmund C., Carlson, Morgan, Ruff, Laura, Padgett, Claire, Cremer, Karl, Wright, Timothy M., Garg, Rekha, Klassen, Preston, Kamel, Amin
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell May2026
Acceso en línea:Ver este registro en EBSCOhost