Evaluation of Acellular Intact Fish Skin Grafts for Treating Acute and Chronic Wounds.
Acute, chronic, and hard‐to‐heal wounds pose a growing challenge due to reduced patient quality‐of‐life, higher cost and increased hospital admissions. Although there is no gold standard for wound care, there is a trend toward simple, outpatient‐compatible treatment options. Acellular dermal fish sk...
| Publicado en: | International Wound Journal Vol. 23; no. 5; pp. 1 - 13 |
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| Autores principales: | , , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
May2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=194010313&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 194010313 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 17424801 1725 jtl: International Wound Journal issn: 17424801 maglogo: Y pubinfo: dt: May2026 vid: 23 iid: 5 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 194010313 194010313 194010313 10.1111/iwj.70931 194010313 ppf: 1 ppct: 12 formats: tig: atl: Evaluation of Acellular Intact Fish Skin Grafts for Treating Acute and Chronic Wounds. aug: au: Böddeker, Christopher Biermann, Sarah Jansen, Theresa Maria Homey, Bernhard Hoff, Norman‐Philipp affil: Department of Dermatology, University Hospital Duesseldorf, Medical Faculty, Heinrich‐Heine‐University Duesseldorf, Duesseldorf, Germany sug: subj: Wounds, Chronic Therapy Fish Skin Transplantation Xenografts Surgery, Operative Quality of Life Treatment Outcomes Human Male Female Middle Age Aged Aged, 80 and Over Retrospective Design Record Review Wound Healing Photography Microscopy Patient Satisfaction Structured Questionnaires Pyoderma Gangrenosum Patient-Reported Outcomes Nonexperimental Studies Questionnaires Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: Acute, chronic, and hard‐to‐heal wounds pose a growing challenge due to reduced patient quality‐of‐life, higher cost and increased hospital admissions. Although there is no gold standard for wound care, there is a trend toward simple, outpatient‐compatible treatment options. Acellular dermal fish skin derived from Gadus morhua (Atlantic cod) is a promising alternative. This retrospective study evaluated the surgical procedures and outcomes associated with fish‐skin graft transplantation for difficult‐to‐treat wounds. Forty‐four patients (33 male and 11 female; mean age: 72.4 years; mean wound area: 84.5 cm2) were treated with acellular fish skin graft. Wound healing was assessed by photographic documentation, confocal microscopy and clinical evaluation. Patient satisfaction was assessed using a structured questionnaire. A positive effect on wound healing, defined as a reduction in wound size, was observed in 88.6% of cases, with complete wound closure in 45.45% of cases. Most patients reported that the procedure was neither painful nor time‐intensive; 95% stated that they would opt for treatment again. Fish skin grafting has also shown beneficial outcomes in complex cases, such as in wounds secondary to pyoderma gangrenosum and wounds with exposed bone. Fish skin graft transplantation represents a safe, well‐tolerated and effective option for managing chronic wounds as well as challenging postoperative wounds, such as those at anatomically challenging sites. Highlights: High healing response in real‐world complex wounds.Effective even in anatomically difficult and high‐risk wounds.Minimally invasive, outpatient‐compatible procedure.Excellent safety profile with no major complications.Strong patient acceptance (95% would repeat treatment).Potential to avoid more invasive reconstructive procedures.Evidence for use in rare inflammatory ulcerative conditions. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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