Nopal Cladode (Opuntia ficus-indica) Fiber Supplementation and Lipid Profile in Dyslipidemic Adults: A Randomized Controlled Trial.

Opuntia ficus-indica is a traditionally consumed cactus rich in dietary fiber and has been associated with potential hypolipidemic effects. Nevertheless, there are still few clinical investigations assessing powder made from highly mature cladodes. The effects of insoluble fiber–rich powder obtained...

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Publicado en:Current Research in Nutrition & Food Science Vol. 14; no. 1; pp. 422 - 438
Autores principales: GÓMEZ-BECERRA, KARLA IVETTE, AGUILERABARREIRO, MARÍA DE LOS ANGELES, CONTRERAS-PADILLA, MARGARITA, MARTÍNEZ-GONZÁLEZ, ÓSCAR, GARRIDO-GUERRERO, GRISSEL, RODRÍGUEZ-GARCÍA, MARIO ENRIQUE, FABELA-ILLESCAS, HÉCTOR ENRIQUE, CHÁVEZ-SERVÍN, JORGE LUIS
Formato: research tables/charts randomized controlled trial Journal Article
Publicado: Current Research in Nutrition & Food Science Apr2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2026
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      pub: Current Research in Nutrition & Food Science
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        10.12944/CRNFSJ.14.1.29
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        atl: Nopal Cladode (Opuntia ficus-indica) Fiber Supplementation and Lipid Profile in Dyslipidemic Adults: A Randomized Controlled Trial.
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        au:
          GÓMEZ-BECERRA, KARLA IVETTE
          AGUILERABARREIRO, MARÍA DE LOS ANGELES
          CONTRERAS-PADILLA, MARGARITA
          MARTÍNEZ-GONZÁLEZ, ÓSCAR
          GARRIDO-GUERRERO, GRISSEL
          RODRÍGUEZ-GARCÍA, MARIO ENRIQUE
          FABELA-ILLESCAS, HÉCTOR ENRIQUE
          CHÁVEZ-SERVÍN, JORGE LUIS
        affil: Faculty of Natural Sciences, Universidad Autónoma de Querétaro, Querétaro, Mexico.
      sug:
        subj:
          Dietary Fiber Pharmacodynamics
          Dietary Supplementation
          Lipids Metabolism
          Hyperlipidemia Diet Therapy
          Obesity Diet Therapy
          Dietary Supplements
          Dietary Fiber Therapeutic Use
          Treatment Outcomes
          Human
          Mexico
          Male
          Female
          Adult
          Middle Age
          Randomized Controlled Trials
          Random Assignment
          Prospective Studies
          Abdominal Fat
          Body Mass Index
          Anthropometry
          Waist Circumference
          Electric Impedance
          Body Composition
          Cholesterol Blood
          Lipoproteins, LDL Cholesterol
          Lipoproteins, HDL Cholesterol
          Triglycerides
          Descriptive Statistics
          Data Analysis Software
          One-Way Analysis of Variance
          Kruskal-Wallis Test
          Paired T-Tests
          Wilcoxon Signed Rank Test
          Repeated Measures
          Confidence Intervals
          Dietary Fiber Administration and Dosage
          Patient Compliance
          Bloat
          Flatulence
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Opuntia ficus-indica is a traditionally consumed cactus rich in dietary fiber and has been associated with potential hypolipidemic effects. Nevertheless, there are still few clinical investigations assessing powder made from highly mature cladodes. The effects of insoluble fiber–rich powder obtained from highly mature Opuntia ficus-indica cladodes (>1000 g) on lipid parameters in overweight or obese adults with dyslipidemia were assessed in this randomized controlled study. Thirty-five participants were randomly assigned to receive 5 g/day (G1) or 15 g/day (G2) of nopal powder combined with dietary counseling, or dietary counseling alone (control group), for 12 weeks. Dietary guidance aimed to achieve an approximate total fiber intake of 30 g/day. The nopal powder contained 49.5% total dietary fiber, predominantly insoluble. Within-group analyses showed significant reductions in total cholesterol (TC) and low-density lipoprotein cholesterol (LDL) in both supplemented groups, while high-density lipoprotein cholesterol (HDL) increased in all groups. Triglycerides (TG) levels decreased significantly in the higher-dose group and in the control group (CG). However, no statistically significant differences were observed between groups at the end of the intervention (p > 0.05). Adherence to the intervention exceeded 80%, and reported gastrointestinal effects were mild and transient. Increased dietary fiber intake during the intervention period was associated with improvements in lipid parameters. However, supplementation with nopal powder did not confer additional statistically significant benefits compared with dietary counseling alone. Nevertheless, powder derived from highly mature Opuntia ficus-indica cladodes represents a concentrated source of dietary fiber that may contribute to increasing fiber intake in populations with low habitual consumption. Further investigations involving larger sample sizes are required to clarify potential dose-dependent effects.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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