Data-Driven and Expert-Informed Causal Discovery for Type 2 Diabetes Risk in Primary Care...36th Medical Informatics Europe (MIE) Conference, May 25-28, 2026, Genoa, Italy.

The aim of this study is to extract causal relationships from a large set of routinely collected primary care data (biomarkers, medical conditions, risk factors, and medications) from across Canada, with a focus on Type 2 Diabetes risk. The causal discovery process combined data-driven insights with...

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Publicado en:Studies in Health Technology & Informatics Vol. 336; pp. 298 - 303
Autores principales: AZZIMONTI, Laura, LENATTI, Marta, ZAFFALON, Marco, SIMEONE, Davide, GUERGACHI, Aziz, KESHAVJEE, Karim, MONGELLI, Maurizio, PAGLIALONGA, Alessia
Formato: proceedings research tables/charts Journal Article
Publicado: Sage Publications Inc. 2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2026
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        atl: Data-Driven and Expert-Informed Causal Discovery for Type 2 Diabetes Risk in Primary Care...36th Medical Informatics Europe (MIE) Conference, May 25-28, 2026, Genoa, Italy.
      aug:
        au:
          AZZIMONTI, Laura
          LENATTI, Marta
          ZAFFALON, Marco
          SIMEONE, Davide
          GUERGACHI, Aziz
          KESHAVJEE, Karim
          MONGELLI, Maurizio
          PAGLIALONGA, Alessia
        affil: IDSIA USI-SUPSI, SUPSI, 6900, Lugano, Switzerland.
      sug:
        subj:
          Primary Health Care Canada
          Diabetes Mellitus, Type 2 Risk Factors
          Risk Assessment
          Causality
          Expert Clinicians
          Data Management
          Electronic Health Records
          Human
          Retrospective Design
          Record Review
          Congresses and Conferences Italy
          Italy
          Canada
          Knowledge
          Diabetes Mellitus, Type 2 Symptoms
          Prediction Models
          Decision Support Systems, Clinical
          Diabetes Mellitus, Type 2 Prevention and Control
          Nonexperimental Studies
          Descriptive Statistics
          Data Analysis Software
          Cholesterol
          Body Mass Index
          Blood Glucose
          ROC Curve
          Confidence Intervals
          Odds Ratio
          Funding Source
      ab: The aim of this study is to extract causal relationships from a large set of routinely collected primary care data (biomarkers, medical conditions, risk factors, and medications) from across Canada, with a focus on Type 2 Diabetes risk. The causal discovery process combined data-driven insights with prior expert knowledge, using iterative refinement to construct a causal Directed Acyclic Graph (DAG). The retrieved DAG, which aligns with medical knowledge and performs satisfactorily in predicting future Type 2 Diabetes onset, could serve as a foundation for developing interpretable tools to support medical decision-making.
      pubtype: Academic Journal
      doctype:
        proceedings
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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