Describing Data Processing in FHIR: AI-Assisted Interoperability for Cancer Stage Extraction...36th Medical Informatics Europe (MIE) Conference, May 25-28, 2026, Genoa, Italy.

Introduction: Creating interoperable clinical data models in FHIR is essential but often labor-intensive. This study explores the use of Generative AI to assist in documenting and structuring FHIR-based data transformation workflows, focusing on TNM cancer staging extraction. Methods: Using FHIR Rel...

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Published in:Studies in Health Technology & Informatics Vol. 336; pp. 884 - 889
Main Authors: OUAGNE, David, ZOSSOU, Vincent, RANCE, Bastien
Format: proceedings research tables/charts Journal Article
Published: Sage Publications Inc. 2026
Online Access:View this record in EBSCOhost
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      dt: 2026
      vid: 336
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      pub: Sage Publications Inc.
      place: Thousand Oaks, California
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        10.3233/SHTI260306
        194018943
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        atl: Describing Data Processing in FHIR: AI-Assisted Interoperability for Cancer Stage Extraction...36th Medical Informatics Europe (MIE) Conference, May 25-28, 2026, Genoa, Italy.
      aug:
        au:
          OUAGNE, David
          ZOSSOU, Vincent
          RANCE, Bastien
        affil: AP-HP, Paris, France.
      sug:
        subj:
          Neoplasm Staging
          Electronic Data Interchange
          Artificial Intelligence, Generative
          Neoplasms Classification
          Health Information Management
          Human
          Congresses and Conferences Italy
          Italy
          Information Storage
          Information Retrieval
          Decision Support Systems, Clinical
          Health Informatics
      ab: Introduction: Creating interoperable clinical data models in FHIR is essential but often labor-intensive. This study explores the use of Generative AI to assist in documenting and structuring FHIR-based data transformation workflows, focusing on TNM cancer staging extraction. Methods: Using FHIR Release 4 and the Plan Definition resource, we modeled transformation processes defined through Business Process Model and Notation (BPMN). The large language model Claude Code (Sonnet 4.5) generated FHIR artifacts from BPMN inputs, which were validated through syntax checks, Implementation Guide compilation, and expert review. Results: AI-assisted generation produced a validated Plan Definition with seven structured activities, accurately representing the TNM extraction workflow. Artifacts were interoperable and passed all FHIR conformance tests after minor revisions. Conclusion / Discussion: Generative AI can effectively support FHIR workflow modeling, reducing complexity and development time. However, expert validation remains essential to ensure semantic accuracy and reproducibility.
      pubtype: Academic Journal
      doctype:
        proceedings
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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