Comparison of Two Instruments to Assess the Impact of Cachexia on Quality of Life in Women with Cervical Cancer.
Cancer-associated cachexia (CAC) is common in cervical cancer (CC) patients. This condition affects the Health-related quality of life (HRQL). This study aims to assess the impact of CAC on HRQL, comparing the Quality of Life Questionnaire (QLQ) QLQ-C30/QLQ-CAX24 and the Functional assessment of ano...
| Published in: | Nutrition & Cancer Vol. 78; no. 6; pp. 410 - 423 |
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| Main Authors: | , , , , |
| Format: | research tables/charts Journal Article |
| Published: |
Taylor & Francis Ltd
2026
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=194088381&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 194088381 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01635581 7MS jtl: Nutrition & Cancer issn: 01635581 maglogo: N pubinfo: dt: 2026 vid: 78 iid: 6 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 194088381 193159336 194088381 194088381 10.1080/01635581.2026.2658765 194088381 ppf: 410 ppct: 13 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Comparison of Two Instruments to Assess the Impact of Cachexia on Quality of Life in Women with Cervical Cancer. aug: au: Luvián-Morales, Julissa Galvan-Cota, Luis Daniel Galvan-Cota, Luis David Castro-Eguiluz, Denisse Oñate-Ocaña, Luis F. affil: Instituto Nacional de Cancerología (INCan), Modelo Integral para la Atención del Cáncer Cervicouterino Localmente Avanzado y Avanzado (MICAELA), Mexico City, Mexico sug: subj: Cervix Neoplasms Complications Cachexia Psychosocial Factors Quality of Life Evaluation Human Female Cancer Patients Psychosocial Factors Comparative Studies Questionnaires Overall Survival Prospective Studies Mexico Middle Age Scales Spearman's Rank Correlation Coefficient Kruskal-Wallis Test Mann-Whitney U Test Kaplan-Meier Estimator Log-Rank Test Cox Proportional Hazards Model Data Analysis Software Middle Aged: 45-64 years Female ab: Cancer-associated cachexia (CAC) is common in cervical cancer (CC) patients. This condition affects the Health-related quality of life (HRQL). This study aims to assess the impact of CAC on HRQL, comparing the Quality of Life Questionnaire (QLQ) QLQ-C30/QLQ-CAX24 and the Functional assessment of anorexia/cachexia therapy (FAACT) instruments. A cohort of CC patients answered the QLQ-C30/QLQ-CAX24 and the FAACT instruments between October 2020 and October 2021. The psychometric/clinimetric characteristics of the instruments were compared. 244 CC patients were included in the study. Correlations between scales ranged from 0.008 to 0.81. The summary score of QLQ-C30 correlated well with the FAACT total score (r = 0.684) and the FAACT Physical Well-being subscale (r = 0.81). The correlation with five nutritional parameters and prognostic indices was poor (r < 0.364). Most symptom scales of the QLQ-CAX24 presented a floor effect, and those of the FAACT did not. The Nausea/vomiting score of the QLQ-C30, and the Loss of control and Forced to eat scales of the QLQ-CAX24 were independently associated with overall survival. The QLQ-C30/QLQ-CAX24 and FAACT instruments differ substantially, but some scales are comparable. We propose an algorithm to select the appropriate instrument to asses HRQL for a research protocol. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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