Overcoming Acquired MET-Driven Resistance to First-Line Lorlatinib: Successful Combination of Lorlatinib and Envafolimab in an ALK-Positive NSCLC Patient with Ultra-High PD-L1 Expression.

Simple Summary: Targeted therapy has significantly improved outcomes for patients with anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC); however, the emergence of resistance remains an inevitable clinical challenge. Standard treatment after progression on third-generation...

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Bibliographic Details
Published in:Current Oncology Vol. 33; no. 5; pp. 258 - 268
Main Authors: Ding, Lu, Nuersulitan, Reyizha, Wang, Jingjing, Chen, Hanxiao, Zhuo, Minglei
Format: Journal Article
Published: MDPI May2026
Online Access:View this record in EBSCOhost